5-甲氧基-2-甲基苯甲酸合成路线 （共 28 条）
反应条件
dipotassium hydrogenphosphate; silver carbonate; p-benozquinone; palladium diacetate in tert-butyl alcohol T=100°C; 3 h;
参考文献
Giri, Ramesh; Maugel, Nathan; Li, Jiao-Jie; Wang, Dong-Hui; Breazzano, Steven P.; Saunders, Lindsey B.; Yu, Jin-Quan
Journal of the American Chemical Society, 2007 , vol. 129, # 12 p. 3510 - 3511
反应条件
potassium hydroxide in water 16 h; Reflux;
参考文献
Herzog, Beat; Neier, Reinhard
Arkivoc, 2011 , vol. 2011, # 6 p. 29 - 44
反应条件
1: s-BuLi; TMEDA / tetrahydrofuran / 0.5 h / -30 °C 2: 0.090 g / aq. HCl / 20 °C / pH 1 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 9 p. 3419 - 3429
反应条件
1: 75 percent / lithium 2,2,6,6-tetramethylpiperidine / tetrahydrofuran / -78 - 20 °C 2: s-BuLi; TMEDA / tetrahydrofuran / 0.5 h / -30 °C 3: 0.090 g / aq. HCl / 20 °C / pH 1 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 72, # 9 p. 3419 - 3429
反应条件
1: acetonitrile 2: NaNH2, liq. NH3 3: aq. NaOH, KMnO4 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 25, p. 334 - 343
反应条件
1: PBr3 / diethyl ether 2: acetonitrile 3: NaNH2, liq. NH3 4: aq. NaOH, KMnO4 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 25, p. 334 - 343
反应条件
Boc-Phe-OH; palladium diacetate; lithium carbonate; silver carbonate; p-benozquinone in tert-butyl alcohol T=90°C; 12 h; Inert atmosphere; Reagent/catalyst;
参考文献
Rosen, Brandon R.; Simke, Leah R.; Thuy-Boun, Peter S.; Dixon, Darryl D.; Yu, Jin-Quan; Baran, Phil S.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 28 p. 7317 - 7320
Angew. Chem., 2013 , vol. 125, # 28 p. 7458 - 7461,4
反应条件
1.1: sulfuric acid / water / 2.5 h / 160 °C 1.2: 2.5 h / 190 °C 2.1: potassium hydroxide / water / 16 h / Reflux View Scheme
参考文献
Arkivoc, , vol. 2011, # 6 p. 29 - 44
参考文献
Journal of Organic Chemistry, , vol. 20, p. 401,407
反应条件
pyridine; potassium permanganate
参考文献
Journal of Organic Chemistry, , vol. 28, p. 2804 - 2806
