N-苄氧羰基-L-天冬氨酸4-甲酯合成路线 （共 14 条）
反应条件
potassium carbonate in diethyl ether; water T=20°C; 4 h;
参考文献
European Journal of Organic Chemistry, , # 17 p. 3387 - 3397
反应条件
lithium hydroxide in tetrahydrofuran T=0°C; Hydrolysis; 2 h;
参考文献
Tetrahedron, , vol. 53, # 48 p. 16575 - 16596
反应条件
pyridine in dichloromethane T=0°C; 18 h; var.time, var. reag.:Et3N, or add of cat.: DMAP; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
pyridine in dichloromethane T=0°C; 24 h; Yields of byproduct given;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
pyridine in dichloromethane T=0°C; 24 h; Yield given. Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
potassium carbonate in water; acetone 2 h; Ambient temperature;
参考文献
Tetrahedron, , vol. 51, # 31 p. 8525 - 8544
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 833 - 834
反应条件
triethylamine in dichloromethane T=0°C; 2 h; add of cat.: DMAP, 1 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 28, # 15 p. 1665 - 1668
反应条件
1: 89 percent / KHCO3 / dimethylformamide / 12 h / 22 °C 2: 91 percent / aq. LiOH / tetrahydrofuran / 2 h / 0 °C View Scheme
参考文献
Tetrahedron, , vol. 53, # 48 p. 16575 - 16596
反应条件
1: 88 percent / H2SO4 / CH2Cl2 / 24 h / 20 °C 2: 43 percent / NaOH / methanol / 3 h / 20 °C 3: NMM / CH2Cl2 / 0.25 h / -10 °C 4: 640 mg / NaBH4 / tetrahydrofuran; H2O / 3.5 h / 20 °C 5: 63.5 mg / acetonitrile / 3 h / 20 °C 6: TFA / CH2Cl2 View Scheme
参考文献
Cox; Wang
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 17 p. 2022 - 2034
