10,11-二氢二苯并[b,f][1,4]噁杂-11-酮合成路线 （共 34 条）
反应条件
palladium complexed dendrimer; N-ethyl-N,N-diisopropylamine in toluene T=80°C; P=5171.48 Torr; 22 h;
参考文献
Yang, Qian; Cao, Hong; Robertson, Al; Alper, Howard
Journal of Organic Chemistry, 2010 , vol. 75, # 18 p. 6297 - 6299
反应条件
1: With tert.-butylnitrite in N,N-dimethyl-formamide T=50°C; 0.666667 h; 2: With hydrogenchloride; water in N,N-dimethyl-formamide
参考文献
MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
Patent: WO2006/97449 A1, 2006 ;
Location in patent: Page/Page column 16 ;
参考文献
Yakugaku Zasshi, , vol. 75, p. 1138
Chem.Abstr., , p. 5561
反应条件
iron in acetic acid Heating;
参考文献
Bunce, Richard A.; Schammerhorn, James E.
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 1031 - 1035
反应条件
tris-(dibenzylideneacetone)dipalladium(0); ammonia; caesium carbonate; [2'-(di-tert-butyl-phosphanyl)-biphenyl-2-yl]-dimethyl-amine in 1,4-dioxane T=120°C; 24 h; Inert atmosphereMolecular sieve;
参考文献
Tsvelikhovsky, Dmitry; Buchwald, Stephen L.
Journal of the American Chemical Society, 2011 , vol. 133, # 36 p. 14228 - 14231
反应条件
potassium carbonate in N,N-dimethyl-formamide T=150°C; 1.5 h;
参考文献
Samet; Kislyi; Marshalkin; Semenov
Russian Chemical Bulletin, 2006 , vol. 55, # 3 p. 549 - 553
反应条件
potassium methanolate in various solvent(s) T=275°C;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 10 p. 1887 - 1897
反应条件
1: SnCl2*2H2O / ethyl acetate / 18 h / 20 °C 2: 99 percent / diisopropylethylamine; palladium complexed dendrimer / toluene / 22 h / 80 °C / 5171.48 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 42 p. 14776 - 14784
反应条件
1: K2CO3 / dimethylsulfoxide / 8 h / 100 °C 2: SnCl2*2H2O / ethyl acetate / 18 h / 20 °C 3: 99 percent / diisopropylethylamine; palladium complexed dendrimer / toluene / 22 h / 80 °C / 5171.48 Torr View Scheme
参考文献
Journal of the American Chemical Society, , vol. 127, # 42 p. 14776 - 14784
反应条件
1: 93 percent / K2CO3 / 10 h / Heating 2: 82 percent / H2 / Raney nickel W-2 / methanol / 3620.13 Torr 3: 3.4 g / H2SO4 / dimethylformamide / 15 h / Heating View Scheme
参考文献
Heterocyclic Communications, , vol. 13, # 2-3 p. 165 - 172
