(2S)-2-羟基-N,N-二甲基丙酰胺合成路线 （共 11 条）
反应条件
methanol T=0 - 60°C; 20 h; Inert atmosphere;
参考文献
LG Chem, Ltd.; Yoon, Sung-Cheol; Park, Seung-Young; Lee, In-Su
Patent: US2013/79547 A1, 2013 ;
Location in patent: Paragraph 0069; 0070 ;
反应条件
T=25 - 160°C; 16 h; Autoclave;
参考文献
Vidal, Thierry; Guglieri, Massimo; Jentzer, Olivier
Patent: US2012/302791 A1, 2012 ;
Location in patent: Page/Page column 22 ;
反应条件
1: With hydroquinone T=60°C; 1.5 h; 2: T=170°C; 2.83333 h; Product distribution / selectivity;
参考文献
SAMSUNG FINE CHEMICALS CO., LTD.; SONG, Won Seob; WOO, Sung Yul; SONG, Boo Weon; KWON, Myong Suk
Patent: WO2012/67470 A2, 2012 ;
Location in patent: Page/Page column 5; 6 ;
参考文献
Craciun, Liliana; Benn, Gerald P.; Dewing, John; Schriver, George W.; Peer, William J.; Siebenhaar, Bernd; Siegrist, Urs
Patent: US2005/222458 A1, 2005 ;
Location in patent: Page/Page column 10 ;
反应条件
ethanol; zinc(II) chloride; zinc 1 h; Heating;
参考文献
Toda, Fumio; Tanaka, Koichi; Tange, Hiroshi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1555 - 1556
反应条件
in water T=20°C; 48 h;
参考文献
Shipov; Gruener; Korlyukov; Kramarova; Murasheva; Bylikin, S. Yu.; Negrebetskii, Vad. V.; Ivashchenko; Airapetyan; Zueva, G. Ya.; Antipin, M. Yu.; Baukov, Yu. I.
Russian Chemical Bulletin, 2010 , vol. 59, # 4 p. 761 - 770
反应条件
(i) LDA, THF, (ii) O2; Multistep reaction;
参考文献
Wasserman,H.H.; Lipshutz,B.H.
Tetrahedron Letters, 1975 , p. 1731 - 1734
反应条件
1: concentrated H2SO4 2: 500 - 530 °C View Scheme
参考文献
Craciun, Liliana; Benn, Gerald P.; Dewing, John; Schriver, George W.; Peer, William J.; Siebenhaar, Bernd; Siegrist, Urs
Patent: US2005/222458 A1, 2005 ;
Location in patent: Page/Page column 10 ;
反应条件
tetrabutylammomium bromide; sodium hydroxide in dichloromethane; water
T=20 - 25°C; 17 h;
参考文献
Vidal, Thierry; Guglieri, Massimo; Jentzer, Olivier
Patent: US2012/302791 A1, 2012 ;
Location in patent: Page/Page column 22 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
2 h; Heating;
参考文献
Brine, George A.; Boldt, Karl G.; Prakash, Doriswamy; Kotchmar, Dennis J.; Bondeson, Virginia C.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 8 p. 1809 - 1814
