1,3-二甲基-2-喹噁啉酮合成路线 （共 22 条）
参考文献
Lawrence; Copper; Smith
Journal of Medicinal Chemistry, 2001 , vol. 44, # 4 p. 594 - 601
反应条件
2,2'-azo-bisisobutyronitrile; tri-n-butyl-tin hydride in benzene T=80°C;
参考文献
Bencivenni, Giorgio; Lanza, Tommaso; Leardini, Rino; Minozzi, Matteo; Nanni, Daniele; Spagnolo, Piero; Zanardi, Giuseppe
Journal of Organic Chemistry, 2008 , vol. 73, # 12 p. 4721 - 4724
反应条件
1: 3-methylbenzo-1H-dihydropyrazine-2-one With sodium hydride in N,N-dimethyl-formamide T=0°C; 0.0833333 h; 2: MeX in N,N-dimethyl-formamide T=0°C; 2 h;
参考文献
Xue, Zhou-Yang; Jiang, Yan; Peng, Xiao-Zhi; Yuan, Wei-Cheng; Zhang, Xiao-Mei
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 13 p. 2132 - 2136
反应条件
copper(l) iodide; 1,10-phenanthroline; caesium carbonate; toluene-4-sulfonamide in 1,4-dioxane T=20 - 100°C; 18.25 h; Inert atmosphere;
参考文献
Chen, Dingben; Wang, Zhi-Jing; Bao, Weiliang
Journal of Organic Chemistry, 2010 , vol. 75, # 16 p. 5768 - 5771
反应条件
potassium carbonate in N,N-dimethyl-formamide T=135°C; 0.333333 h;
参考文献
Cazaux, Louis; Faher, Mourad; Picard, Claude; Tisnes, Pierre
Canadian Journal of Chemistry, 1993 , vol. 71, # 12 p. 2007 - 2015
反应条件
potassium carbonate in acetone Heating;
参考文献
Badr; El-Naggar; El-Sherief; Mahgoub
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 6 p. 1653 - 1657
反应条件
hydrazine hydrate 1 h; Heating;
参考文献
Klicnar, Jiri; Toman, Jaromir
Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 9 p. 2110 - 2115
反应条件
1: 20 percent / K2CO3 / bromure de tetra n-butylammonium / dimethylformamide 2: 80 percent / Br2, NaOAc / acetic acid / 1 h / Ambient temperature 3: 50 percent / H2O; dimethylformamide / 2 h / 20 - 25 °C 4: 30 percent / HCl / aq. HCl / 5 h View Scheme
参考文献
Essassi, El Mokhtar; Ferfra, Souad; Salem, Moussa; Zniber, Rachid
Bulletin des Societes Chimiques Belges, 1990 , vol. 99, # 1 p. 47 - 60
反应条件
HCl in hydrogenchloride 5 h;
参考文献
Essassi, El Mokhtar; Ferfra, Souad; Salem, Moussa; Zniber, Rachid
Bulletin des Societes Chimiques Belges, 1990 , vol. 99, # 1 p. 47 - 60
反应条件
1: 100 percent / ethanol / 4 h / Heating 2: 60 percent / K2CO3 / dimethylformamide / 0.33 h / 135 °C View Scheme
参考文献
Cazaux, Louis; Faher, Mourad; Picard, Claude; Tisnes, Pierre
Canadian Journal of Chemistry, 1993 , vol. 71, # 12 p. 2007 - 2015
