(6Z)-8-甲基-6-壬烯酸合成路线 （共 10 条）
反应条件
potassium hydroxide in ethanol 1 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 53, # 5 p. 1064 - 1071
反应条件
1: conc. H2SO4 / Heating 2: pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1.5 h / Ambient temperature 3: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h 4: aq. KOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 5 p. 1064 - 1071
反应条件
1: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h 2: aq. KOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 5 p. 1064 - 1071
反应条件
1: pyridinium chlorochromate (PCC), sodium acetate / CH2Cl2 / 1.5 h / Ambient temperature 2: 1.) t-BuOK / 1.) DMF, RT, 5 min, 2.) a) RT, 20 h, b) 90 deg C, 1 h 3: aq. KOH / ethanol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 5 p. 1064 - 1071
反应条件
potassium tert-butylate in N,N-dimethyl-formamide 15 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 54, p. 3477 - 3478
反应条件
1: 2M NaNO2, 5M aq. HNO3 / 0.5 h / 70 - 75 °C 2: thionyl chloride / 1.) room temp., 8 h, 2.) 100 deg C, 0.5 h 3: diethyl ether / 1.) RT, 2 h, 2.) reflux, 2 h View Scheme
参考文献
Kaga, Harumi; Miura, Masakatsu; Orito, Kazuhiko
Journal of Organic Chemistry, 1989 , vol. 54, p. 3477 - 3478
反应条件
1: nitric acid; sodium nitrite / water / 1.5 h / 70 °C / Inert atmosphere 2: thionyl chloride / 1 h / 60 °C 3: pyridine / 18 h / Inert atmosphere 4: hydrogenchloride; water / ethanol / 18 h / 20 °C / Inert atmosphere View Scheme
参考文献
Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
反应条件
1: 2M NaNO2, 5M aq. HNO3 / 0.5 h / 70 - 75 °C 2: thionyl chloride / 1.) room temp., 8 h, 2.) 100 deg C, 0.5 h View Scheme
参考文献
Barbero, Gerardo F.; Molinillo, Jose M. G.; Varela, Rosa M.; Palma, Miguel; MacIas, Francisco A.; Barroso, Carmelo G.
Journal of Agricultural and Food Chemistry, 2010 , vol. 58, # 6 p. 3342 - 3349
反应条件
1: thionyl chloride / 1.) RT, 18 h, 2.) 100 deg C, 30 min 2: diethyl ether / 72 h / Ambient temperature 3: H2 / 10percent Pd/C / ethanol / 4 h / 760 Torr View Scheme
参考文献
Gannett, Peter M.; Nagel, Donald L.; Reilly, Pam J.; Lawson, Terence; Sharpe, Jody; Toth, Bela
Journal of Organic Chemistry, 1988 , vol. 53, # 5 p. 1064 - 1071
反应条件
1: oxalyl chloride / 3 h 2: 70 percent / dimethylformamide; diethyl ether View Scheme
参考文献
Gannett, Peter M.; Nagel, Donald L.; Reilly, Pam J.; Lawson, Terence; Sharpe, Jody; Toth, Bela
Journal of Organic Chemistry, 1988 , vol. 53, # 5 p. 1064 - 1071
