3-烯丙基-2-羟基苯甲酸甲酯合成路线 （共 36 条）
反应条件
1: sodium methylate
2: 250 °C
3: sodium methylate
4: methanol. NaOH-solution
5: >100
View Scheme
参考文献
Claisen
Justus Liebigs Annalen der Chemie, 1919 , vol. 418, p. 102
反应条件
1: aniline
2: K2CO3; acetone
3: beim Erhitzen in CO2-Atmosphaere
4: hydrogen; colloidal palladium; alcohol
View Scheme
参考文献
Claisen
Justus Liebigs Annalen der Chemie, 1919 , vol. 418, p. 102
反应条件
1: sodium methylate
2: 250 °C
View Scheme
参考文献
Claisen; Eisleb
Justus Liebigs Annalen der Chemie, 1913 , vol. 401, p. 44
参考文献
Adams; Rindfusz
Journal of the American Chemical Society, 1919 , vol. 41, p. 661
反应条件
Yield given. Multistep reaction;
参考文献
Stanetty, Peter; Koller, Herbert; Puerstinger, Gerhard
Monatshefte fuer Chemie, 1990 , vol. 121, # 11 p. 883 - 891
反应条件
1: NaH / 1) 20 min at 0 deg C 2) reflux for 12 h
2: NaOH / 1) 1h reflux with NaOH 2) concentrated HCl
3: SOCl2
4: 1) BF3*THF 2) NaOH, 30percent H2O2 / 2) at 55-60 deg C for 90 min
5: 88 percent / triethylamine / CH2Cl2 / 2.5 h / Ambient temperature
6: 100 percent / LiBr / dimethylformamide
7: 80 percent / Mg / tetrahydrofuran / 48 h / Heating
8: 67 percent / 4.5M HCl / 18 h / Heating
View Scheme
参考文献
Meyers, A. I.; Reuman, Michael; Gabel, Richard A.
Journal of Organic Chemistry, 1981 , vol. 46, # 4 p. 783 - 788
