4-乙基-4-羟基-3,4,12,14-四氢-1H-吡喃并[3'4':6,7]吲哚嗪并[1,2-b]喹啉-3,14-二酮合成路线 （共 79 条）
反应条件
1: 1 N HCl / 3 h / Heating 2: 84 percent / DEAD, PPh3 / tetrahydrofuran / Ambient temperature 3: 59 percent / Pd(OAc)2, KOAc / acetonitrile View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 18 p. 5120 - 5121
反应条件
1: (i-PrO)3Al / propan-2-ol / 3 h / Heating 2: 1 N HCl / 3 h / Heating 3: 84 percent / DEAD, PPh3 / tetrahydrofuran / Ambient temperature 4: 59 percent / Pd(OAc)2, KOAc / acetonitrile View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 18 p. 5120 - 5121
反应条件
1: 84 percent / DEAD, PPh3 / tetrahydrofuran / Ambient temperature 2: 59 percent / Pd(OAc)2, KOAc / acetonitrile View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 18 p. 5120 - 5121
反应条件
1: 43 percent / SeO2 / dioxane; H2O / 4 h / 160 °C 2: 45 percent / pyridinium dichromate, 4-Angstroem molecular sieves / CH2Cl2 / 3.5 h / 0 °C 3: 80 percent / p-TsOH / toluene / 3.5 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 611 - 617
反应条件
1: 94 percent / benzene; methanol; hexane / 3 h 2: 75 percent / p-TsOH / toluene / 4 h / Heating 3: 71 percent / 48percent aq. HBr / 15 h / 140 °C 4: 91 percent / O2, CuCl2, dimethylamine / dimethylformamide / 7 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 611 - 617
反应条件
1: 75 percent / p-TsOH / toluene / 4 h / Heating 2: 71 percent / 48percent aq. HBr / 15 h / 140 °C 3: 91 percent / O2, CuCl2, dimethylamine / dimethylformamide / 7 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 611 - 617
反应条件
1: 1) O3, 2) Me2S / 1) MeOH, CH2Cl2, O3, -70 deg C, 2) -70 deg C to room temperature, 12 h 2: 94 percent / benzene; methanol; hexane / 3 h 3: 75 percent / p-TsOH / toluene / 4 h / Heating 4: 71 percent / 48percent aq. HBr / 15 h / 140 °C 5: 91 percent / O2, CuCl2, dimethylamine / dimethylformamide / 7 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 611 - 617
反应条件
1: 71 percent / 48percent aq. HBr / 15 h / 140 °C 2: 91 percent / O2, CuCl2, dimethylamine / dimethylformamide / 7 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 58, # 3 p. 611 - 617
反应条件
1: H2SO4 / ethanol; H2O 2: (i) NaH, DMF, (ii) /BRN= 505934/ 3: air / CH2Cl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 38, # 11 p. 1974 - 1982
反应条件
sodium methylate in methanol 8 h; Ambient temperature;
参考文献
Tetrahedron Letters, , vol. 35, # 21 p. 3613 - 3616
