2,4-二-(alpha-甲氧基乙基)次卟啉-Ix二钾盐合成路线 （共 5 条）
反应条件
sodium hydroxide in 1,4-dioxane T=70°C; 1 h;
参考文献
Borovkov, V. V.; Gribkov, A. A.; Evstigneeva, R. P.; Struganova, I. A.; Ponomarev, G. V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 10 p. 1059 - 1064
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , vol. 27, # 10 p. 1324 - 1330
反应条件
1: Hematoporphyrin IX With hydrogen bromide; acetic acid 4 h; 2: methanol T=60°C; 24 h; 3: With sodium hydroxide in methanol T=20°C;
参考文献
Kim, Yeong-Sang; Song, Rita; Kim, Dong Hyun; Jun, Moo Jin; Sohn, Youn Soo
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 8 p. 1753 - 1760
反应条件
1: 12 h / 20 °C 2: 94 percent / aq. NaOH / dioxane / 1 h / 70 °C View Scheme
参考文献
Tao, Fei Y.; Wang, Chang G.; Ma, Kuo Y.; Li, Dong L.; Tan, Lan L.; Zhang, Ji; Dai, Ya; Yu, Xiao Q.
Journal of Porphyrins and Phthalocyanines, 2013 , vol. 17, # 4 p. 309 - 316
反应条件
1: aq. HBr (d 1.45) / acetic acid / 72 h 2: 12 h / 20 °C 3: 94 percent / aq. NaOH / dioxane / 1 h / 70 °C View Scheme
参考文献
Borovkov, V. V.; Gribkov, A. A.; Evstigneeva, R. P.; Struganova, I. A.; Ponomarev, G. V.; et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 10 p. 1059 - 1064
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , vol. 27, # 10 p. 1324 - 1330
参考文献
Chen, Zhi-Long; Wan, Wei-Qin; Chen, Jing-Rong; Zhao, Fang; Xu, De-Yu
Heterocycles, 1998 , vol. 48, # 9 p. 1739 - 1745
