1: thiophene With n-butyllithium in tetrahydrofuran; hexane T=0°C; 1 h; 2: With zinc(II) chloride in tetrahydrofuran; hexane T=0°C; 1 h; 3: 2,3,5-tribromothiophene With [Pd(en)Cl2] in tetrahydrofuran; hexane T=20°C; regioselective reaction;
参考文献
Amb, Chad M.; Rasmussen, Seth C.
European Journal of Organic Chemistry, 2008 , # 5 p. 801 - 804
n-butyllithium in tetrahydrofuran; hexane 1.) -70 deg C, 10 min, 2.) -70 deg C -> 0 deg C;
参考文献
Hawkins, David W.; Iddon, Brian; Longthorne, Darren S.; Rosyk, Peter J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2735 - 2744
Hawkins, David W.; Iddon, Brian; Longthorne, Darren S.; Rosyk, Peter J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 19 p. 2735 - 2744
