1,7-偶氮-15-冠-5合成路线 （共 17 条）
反应条件
1: 80 percent / NaN3 / aq. ethanol / 1.)60 deg C, 1 h 2.)reflux, 8-10 h 2: 82 percent / lithium aluminum hydride / tetrahydrofuran / 10 h / Heating 3: 60 percent / toluene / 1.)0 deg C, 7 h 2.)overnight 4: 85 percent / lithium aluminum hydride / tetrahydrofuran / 8 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 18, p. 297 - 302
反应条件
1: 78 percent / pyridine / 1.5 h 2: 80 percent / NaN3 / aq. ethanol / 1.)60 deg C, 1 h 2.)reflux, 8-10 h 3: 82 percent / lithium aluminum hydride / tetrahydrofuran / 10 h / Heating 4: 60 percent / toluene / 1.)0 deg C, 7 h 2.)overnight 5: 85 percent / lithium aluminum hydride / tetrahydrofuran / 8 h / Heating View Scheme
参考文献
Journal of Heterocyclic Chemistry, , vol. 18, p. 297 - 302
反应条件
1: tetrabutylammonium iodide, sodium hydroxide (50 percent) / toluene; H2O / 9 h / Heating 2: 88 percent / lithium aluminum hydride / tetrahydrofuran / 20 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 24, p. 1562 - 1571
Zhurnal Organicheskoi Khimii, , vol. 24, # 8 p. 1731 - 1742
反应条件
1: 70 percent / methanol / 168 h / 25 °C / 750.06 Torr 2: 80 percent / lithium aluminium hydride (LAH) / tetrahydrofuran / 24 h / Heating View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 14 p. 956 - 957
反应条件
sodium carbonate in tetrahydrofuran 96 h; Heating;
参考文献
Anelli, Pier Lucio; Montanari, Fernando; Quici, Silvio
Journal of Organic Chemistry, 1985 , vol. 50, # 19 p. 3453 - 3457
反应条件
1: Et3N 2: B2H6 3: (i) aq. HCl, (ii) ion-exchange resin <OH- form> View Scheme
参考文献
Dietrich,B. et al.
Tetrahedron, 1973 , vol. 29, p. 1629 - 1645
参考文献
Cho, Iwhan; Chang, Suk-Kyu
Chemistry Letters, 1981 , p. 515 - 518
