5-甲基-2-硝基苯甲酸合成路线 （共 50 条）
反应条件
1: tin; hydrochloric acid 2: Diazotization.nachfolgend Erhitzen mit Wasser View Scheme
参考文献
Findeklee
Chemische Berichte, 1905 , vol. 38, p. 3555
反应条件
copper(I) oxide; 1,10-phenanthroline in 1-methyl-pyrrolidin-2-one; quinoline T=190°C; 0.0833333 h; Microwave irradiation;
参考文献
Goossen, Lukas J.; Manjolinho, Filipe; Khan, Bilal A.; Rodriguez, Nuria
Journal of Organic Chemistry, 2009 , vol. 74, # 6 p. 2620 - 2623
反应条件
sulfuric acid in methanol 48 h; Heating / reflux;
参考文献
US2004/214798 A1, ;
Page 17 ;
反应条件
hydrogenchloride 20 h; Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 21, p. 1807 - 1816
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C; 4 h;
参考文献
EP2103601 A1, ;
Page/Page column 35 ;
反应条件
1: 1.) SOCl2; 2.) NH4OH / 1.) PhMe, reflux 2: SOCl2 / Heating 3: 92 percent / 15 percent TiCl3 / acetone; H2O / 0.5 h View Scheme
参考文献
Lamara; Redhouse; Smalley; Thompson
Tetrahedron, 1994 , vol. 50, # 18 p. 5515 - 5525
反应条件
dimethylsulfide borane complex in tetrahydrofuran T=80°C; 3 h; Inert atmosphere;
参考文献
Kong, Chen; Jana, Navendu; Driver, Tom G.
Organic Letters, 2013 , vol. 15, # 4 p. 824 - 827
反应条件
(i) H2, aq. NaOH, Pd-CaCO3, (ii) NaNO2, aq. HCl, (iii) KI, aq. HCl; Multistep reaction;
参考文献
Gore,P.H. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1973 , p. 2940 - 2948
反应条件
1: 1.) SOCl2; 2.) NH4OH / 1.) PhMe, reflux 2: SOCl2 / Heating View Scheme
参考文献
Lamara; Redhouse; Smalley; Thompson
Tetrahedron, 1994 , vol. 50, # 18 p. 5515 - 5525
反应条件
potassium hydroxide; potassium permanganate in water
参考文献
Andrianjara, Charles; Barvian, Nicole Chantel; Gaudilliere, Bernard; Jacobelli, Henri; Ortwine, Daniel Fred; Patt, William Chester; Pham, Ly; Kostlan, Catherine Rose; Wilson, Michael William
Patent: US2002/193377 A1, 2002 ;
US 20020193377 A1
