3-甲基-4-硝基苯甲酸合成路线 （共 68 条）
参考文献
Journal of the Chemical Society, , p. 2245,2247
反应条件
Produktverhaeltnis abhaengig von der Reaktionstemperatur (75 grad / Siedetemperatur);
参考文献
Zhurnal Prikladnoi Khimii (Sankt-Peterburg, Russian Federation), , vol. 5, p. 612,615
Chem. Zentralbl., , vol. 104, # I p. 3441
参考文献
Monatshefte fuer Chemie, , vol. 41, p. 155
参考文献
Journal of the Chemical Society, , p. 1400,1403
反应条件
1.1: thionyl chloride / 1 h / 0 - 80 °C 2.1: hydrogen / palladium on activated charcoal / methanol / 20 °C 3.1: hydrogenchloride; sodium nitrite; NH4BF4 / water / 0.58 h 3.2: 2 h / 20 °C View Scheme
参考文献
US2012/277224 A1, ;
US 20120277224 A1
反应条件
pyridine; benzenesulfonyl chloride 1 h;
参考文献
Affinium Pharmaceuticals, Inc.
Patent: US6762201 B1, 2004 ;
Location in patent: Page/Page column 13 ;
反应条件
pyridine; benzenesulfonyl chloride in hexane; ethyl acetate; tert-butyl alcohol
参考文献
SmithKline Beecham Corporation
Patent: US6117866 A1, 2000 ;
反应条件
1: dimethylsulfide borane complex / tetrahydrofuran / |Reflux 2: palladium on activated charcoal; hydrogen / ethanol / 20 °C 3: potassium acetate; isopentyl nitrite; 18-crown-6 ether / chloroform / |Reflux 4: hydrogen bromide / water / 20 °C 5: tetrahydrofuran / 2 h / |Reflux View Scheme
参考文献
UNIVERSITY OF UTAH RESEARCH FOUNDATION; JI, Haitao; YU, Binxun; ZHANG, Min; GUO, Wenxing
Patent: WO2013/120045 A1, 2013 ;
反应条件
1: iron sulfate(II) hydrate; ammonia 2: lime/chalk/ / bei der Destillation View Scheme
参考文献
Mueller
Chemische Berichte, 1909 , vol. 42, p. 433
反应条件
1.1: sulfuric acid / 16 h / |Reflux 2.1: palladium 10 on activated carbon; ammonium formate / methanol / 3 h / 20 °C / |Inert atmosphere 3.1: potassium acetate / toluene / 0.17 h / |Inert atmosphere; |Reflux 3.2: 16.5 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Hawes, Chris S.; Babarao, Ravichandar; Hill, Matthew R.; White, Keith F.; Abrahams, Brendan F.; Kruger, Paul E.
Chemical Communications, 2012 , vol. 48, # 94 p. 11558 - 11560
