2-[1-(4-氯苯基)亚乙基]丙二腈合成路线 (共 8 条)
反应条件
morpholine in water T=100°C; Knoevenagel condensation; 0.5 h;
参考文献
Mukhopadhyay, Chhanda; Das, Paramita; Butcher, Ray J.
Organic Letters, 2011 , vol. 13, # 17 p. 4664 - 4667
反应条件
triethylamine in water T=100°C; 3 h; SolventTemperatureTimeReagent/catalystConcentration;
参考文献
Das, Paramita; Ray, Suman; Mukhopadhyay, Chhanda
Organic Letters, 2013 , vol. 15, # 22 p. 5622 - 5625
反应条件
10-methyl-9,10-dihydroacridine in acetonitrile T=65°C; 48 h; dark;
参考文献
Liu, You-Cheng; Li, Bin; Guo, Qing-Xiang
Tetrahedron, 1995 , vol. 51, # 35 p. 9671 - 9680
参考文献
Mowry
Journal of the American Chemical Society, 1945 , vol. 67, p. 1050
反应条件
copper(II) bis(trifluoromethanesulfonate); triethylamine in acetonitrile 5 h; Reflux;
参考文献
Su, Weike; Ding, Kai; Chen, Zhiwei
Tetrahedron Letters, 2009 , vol. 50, # 6 p. 636 - 639
反应条件
[BmIm]OH; air in ethanol 4.5 h; Reflux;
参考文献
Chen, Zhiwei; Ding, Kai; Su, Weike
Synthetic Communications, 2011 , vol. 41, # 10 p. 1410 - 1420
反应条件
morpholine; sulfur in N,N-dimethyl-formamide
T=20 - 120°C; Gewald reaction; 0.166667 h;
参考文献
Han, Guang-Fan; Wang, Ming; Chen, Li-Zhuang; Hu, Xiao-Lei
Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 4 p. 909 - 912
反应条件
copper (II) acetate monohydrate in water; acetic acid
T=100°C; 12 h; stereoselective reaction;
参考文献
Xin, Xiaoqing; Xiang, Dexuan; Yang, Jiming; Zhang, Qian; Zhou, Fenguo; Dong, Dewen
Journal of Organic Chemistry, 2013 , vol. 78, # 23 p. 11956 - 11961