2-羟基-5-苄氧基苯乙酮合成路线 （共 14 条）
反应条件
potassium carbonate in acetone 48 h; Reflux;
参考文献
Mays, Jared R.; Hill, Stephanie A.; Moyers, Justin T.; Blagg, Brian S.J.
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 1 p. 249 - 266
反应条件
potassium carbonate; sodium iodide in acetone 15 h; Heating;
参考文献
Bruce, J. Malcolm; Roshan-Ali, Yusuf
Journal of Chemical Research, Miniprint, 1981 , # 7 p. 2564 - 2572
反应条件
MgBr2(Et2O) in diethyl ether; benzene debenzylation; 21 h; Heating;
参考文献
Giles, Robin G. F.; Joli, Cynthia A.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 20 p. 3039 - 3048
反应条件
potassium carbonate; sodium iodide in N,N-dimethyl-formamide T=60°C; 24 h;
参考文献
Giles, Robin G. F.; Joli, Cynthia A.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 20 p. 3039 - 3048
反应条件
in sodium hydroxide; hexane; ethyl acetate; acetone
参考文献
Pfizer Inc.
Patent: US5248685 A1, 1993 ;
参考文献
Pfizer Inc.
Patent: US5248685 A1, 1993 ;
反应条件
1: 99 percent / K2CO3 / acetone / 18 h / Heating 2: 90 percent / magnesium bromide-diethyl ether solution / benzene; diethyl ether / 21 h / Heating View Scheme
参考文献
Giles, Robin G. F.; Joli, Cynthia A.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 20 p. 3039 - 3048
反应条件
1: 89 percent / bis(benzonitrile)palladium(II) chloride / benzene / 20 h / Heating 2: 85 percent / K2CO3, NaI / acetone / 15 h / Heating View Scheme
参考文献
Bruce, J. Malcolm; Roshan-Ali, Yusuf
Journal of Chemical Research, Miniprint, 1981 , # 7 p. 2564 - 2572
参考文献
Hege; Weymann; Lietz
Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 8 p. 843 - 849
反应条件
1: 82 percent / 50percent aq. NaOH / ethanol / 1 h 2: 85.2 percent / H2 / 5percent Pd-C / ethyl acetate 3: NaOH / 1.5 h / Heating 4: 71 percent / Heating 5: 56.3 percent / H2 / 5percent Pd-C / methanol View Scheme
参考文献
Chiba, Peter; Tell, Barbara; Jaeger, Walter; Richter, Elisabeth; Hitzler, Manuela; Ecker, Gerhard
Archiv der Pharmazie, 1997 , vol. 330, # 11 p. 343 - 347
