3-甲氧基-2-甲基-3-氧代丙酸合成路线 （共 6 条）
反应条件
potassium hydroxide in tetrahydrofuran T=0°C; 1.5 h;
参考文献
TEXAS TECH UNIVERSITY
Patent: WO2008/150487 A2, 2008 ;
Location in patent: Page/Page column 17-21; 23 ;
反应条件
1: With potassium hydroxide T=20°C; 2: With hydrogenchloride in water Acidic aqueous solution;
参考文献
FOREST LABORATORIES HOLDINGS LIMITED
Patent: US2009/239848 A1, 2009 ;
Location in patent: Page/Page column 35 ;
US 20090239848 A1
反应条件
boric acid T=20°C; 72 h;
参考文献
Levonis, Stephan M.; Bornaghi, Laurent F.; Houston, Todd A.
Australian Journal of Chemistry, 2007 , vol. 60, # 11 p. 821 - 823
反应条件
hydrogenchloride; sodium; urea in ethanol; water
参考文献
Ciba-Geigy Corporation
Patent: US4741760 A1, 1988 ;
参考文献
Nader, Franz W.; Brecht, Angelika; Kreisz, Siegfried
Chemische Berichte, 1986 , vol. 119, # 4 p. 1196 - 1207
反应条件
diethylamine in water-d2
40 h; Ambient temperature;
参考文献
Hosokawa, Takahiro; Yamanaka, Toshio; Itotani, Motohiro; Murahashi, Shun-Ichi
Journal of Organic Chemistry, 1995 , vol. 60, # 19 p. 6159 - 6167
