4-氨基-3,5-二甲基-苯甲酸甲酯合成路线 （共 7 条）
反应条件
10 palladium on activated carbon in ethyl acetate P=2844.39 Torr; 0.5 h; Catalytic hydrogenation;
参考文献
US6342610 B2, ;
Page column 125 ;
US 6342610 B2
反应条件
hydrogen; nickel in ethanol T=20°C; 1 h;
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 14 p. 3033 - 3044
反应条件
nitric acid; sodium hydrogencarbonate; palladium; N,N-dimethyl-formamide in methanol; acetic acid; ethyl acetate
反应条件
1.1: N-chlorosuccinimide / CH2Cl2 / 0.5 h / 20 °C 1.2: 48 percent / Et3N / 5 h / Heating 2.1: 88 percent / H2 / Raney Ni / ethanol / 1 h / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 14 p. 3033 - 3044
反应条件
1: With N-chloro-succinimide; triethylamine in dichloromethane 2: in ethanol
参考文献
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, , vol. 75, # 1 p. 320 - 324
反应条件
1: thionyl chloride / 16 h / 0 - 80 °C 2: hydrogenchloride; iron / methanol / 16 h / 0 - 80 °C View Scheme
参考文献
Monatshefte fuer Chemie, , vol. 25, p. 1203
