6,7,8-三甲氧基喹唑啉-2,4(1H,3H)-二酮合成路线 （共 4 条）
参考文献
LABORATORIOS DEL DR. ESTEVE S.A.
Patent: WO2006/72588 A1, 2006 ;
Location in patent: Page/Page column 39 ;
反应条件
1: H2 / 5percent Pd/C (50percent water wet) / propan-2-ol / 8 h / 68 - 75 °C / 2068.6 Torr 2: 50percent aq. NaOH / propan-2-ol; H2O / 3 h / Heating 3: H2O / 0 - 5 °C / pH 6.8-7.3 4: 99.5 percent / 50percent aq. NaOH / H2O / 3 h / 55 - 57 °C / pH > 13 View Scheme
参考文献
Hammen; Allen
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1701 - 1703
反应条件
1: 50percent aq. NaOH / propan-2-ol; H2O / 3 h / Heating 2: H2O / 0 - 5 °C / pH 6.8-7.3 3: 99.5 percent / 50percent aq. NaOH / H2O / 3 h / 55 - 57 °C / pH > 13 View Scheme
参考文献
Hammen; Allen
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1701 - 1703
反应条件
1: H2O / 0 - 5 °C / pH 6.8-7.3 2: 99.5 percent / 50percent aq. NaOH / H2O / 3 h / 55 - 57 °C / pH > 13 View Scheme
参考文献
Hammen; Allen
Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 6 p. 1701 - 1703
