(2,3,4,5,6-五氯苯基)3-苯基-2-(苯基甲氧羰基氨基)丙酸酯合成路线 (共 7 条)
反应条件
n-ethyl morpholine; hexamethylphosphorous triamide dichloride in dichloromethane 1) 0 deg C, 2 h, 2) overnight, r.t.;
参考文献
Appel, Rolf; Glaesel, Ursula
Chemische Berichte, 1980 , vol. 113, # 11 p. 3511 - 3516
参考文献
Sakakibara; Inukai
Bulletin of the Chemical Society of Japan, 1965 , vol. 38, # 11 p. 1979 - 1984
反应条件
1: quinoline 2: (i), (ii) DCC View Scheme
参考文献
Wolman,Y. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 689 - 690
反应条件
(i) DMF, (ii) /BRN= 2222826/, Et3N; Multistep reaction;
参考文献
Itoh,M.
Chemical and Pharmaceutical Bulletin, 1970 , vol. 18, # 4 p. 784 - 788
反应条件
(i), (ii) DCC; Multistep reaction;
参考文献
Wolman,Y. et al.
Journal of the Chemical Society [Section] C: Organic, 1967 , p. 689 - 690
反应条件
2-Hydroxypyridine; dicyclohexyl-carbodiimide
参考文献
Kapoor; Davis; Graetzer
Journal of pharmaceutical sciences, 1968 , vol. 57, # 9 p. 1514 - 1519
反应条件
1: DCC, 1H-pyridin-2-one
2: H2 / Pd-C
View Scheme
参考文献
Kapoor; Davis; Graetzer
Journal of pharmaceutical sciences, 1968 , vol. 57, # 9 p. 1514 - 1519