(2S)-2-氨基-3-苯丙酸乙酯合成路线 （共 35 条）
反应条件
triethylamine in diethyl ether
参考文献
Davidovich,Yu.A. et al.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1978 , vol. 27, p. 590 - 592
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1978 , vol. 27, p. 683 - 685
反应条件
sodium acetate; acetic acid
参考文献
Shmatova, Olga I.; Shevchenko, Nikolay E.; Balenkova, Elizabeth S.; Roeschenthaler, Gerd-Volker; Nenajdenko, Valentine G.
Mendeleev Communications, 2013 , vol. 23, # 2 p. 92 - 93
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 70 °C / Inert atmosphere
2: N-ethyl-N,N-diisopropylamine / dichloromethane / Inert atmosphere
3: 10 palladium on activated charcoal; hydrogen / Inert atmosphere
4: carbon tetrabromide; triphenylphosphine / dichloromethane / Inert atmosphere
5: potassium hexamethylsilazane / N,N-dimethyl-formamide / 0.5 h / -60 °C / Inert atmosphere
View Scheme
参考文献
Anxionnat, Bruno; Robert, Benoit; George, Pascal; Ricci, Gino; Perrin, Marc-Antoine; Gomez Pardo, Domingo; Cossy, Janine
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6087 - 6099
反应条件
1: potassium carbonate / N,N-dimethyl-formamide / 70 °C / Inert atmosphere
2: N-ethyl-N,N-diisopropylamine / dichloromethane / Inert atmosphere
3: 10 palladium on activated charcoal; hydrogen / Inert atmosphere
4: carbon tetrabromide; triphenylphosphine / dichloromethane / Inert atmosphere
5: potassium hexamethylsilazane / N,N-dimethyl-formamide / 0.5 h / -60 °C / Inert atmosphere
View Scheme
参考文献
Anxionnat, Bruno; Robert, Benoit; George, Pascal; Ricci, Gino; Perrin, Marc-Antoine; Gomez Pardo, Domingo; Cossy, Janine
Journal of Organic Chemistry, 2012 , vol. 77, # 14 p. 6087 - 6099
反应条件
triethylamine in tetrahydrofuran
Substitution; 1.33333 h; Heating;
参考文献
Kashima, Choji; Tsuruoka, Shiro; Mizuhara, Saori
Heterocycles, 2000 , vol. 52, # 1 p. 413 - 424
