3,4-二氢-2H-1,4-苯并噻嗪合成路线 （共 37 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0°C; 2 h; Under nitrogenHeating / reflux;
参考文献
Al-Awar, Rima Salim; Hecker, Kyle Andrew; Ray, James Edward; Huang, Jianping; Joseph, Sajan; Li, Tiechao; Paal, Michael; Rathnachalam, Radhakrishnan; Shih, Chuan; Waid, Philip Parker; Zhou, Xun; Zhu, Guoxin
Patent: US2003/229026 A1, 2003 ;
Location in patent: Page 21 ;
US 20030229026 A1
反应条件
potassium carbonate; sodium iodide in N,N-dimethyl-formamide T=90°C;
参考文献
Ramnauth, Jailall; Annedi, Subhash C.; Silverman, Sarah; Dove, Peter; Maddaford, Shawn; Rakhit, Suman
Patent: US2010/9975 A1, 2010 ;
Location in patent: Page/Page column 69 ;
US 20100009975 A1
反应条件
potassium carbonate in acetone T=20°C;
参考文献
Duan, Jingwu; Jiang, Bin; Chen, Lihua; Lu, Zhonghui; Barbosa, Joseph; Pitts, William J.
Patent: US2003/229084 A1, 2003 ;
Location in patent: Page/Page column 32; 33 ;
反应条件
1: With diisobutylaluminium hydride in hexane; dichloromethane T=0 - 20°C; Inert atmosphere; 2: With NAF in hexane; dichloromethane; water T=0°C; 0.5 h;
参考文献
Cho, Hidetsura; Iwama, Yusuke; Sugimoto, Kenji; Mori, Seiji; Tokuyama, Hidetoshi
Journal of Organic Chemistry, 2010 , vol. 75, # 3 p. 627 - 636
参考文献
Sheppeck, James E.; Duan, Jingwu; Xue, Chu-Biao; Wasserman, Zelda
Patent: US2003/130273 A1, 2003 ;
US 20030130273 A1
参考文献
Ott, Gregory R.; Chen, Xiao-Tao; Duan, Jingwu; Lu, Zhonghui
Patent: US2003/139388 A1, 2003 ;
反应条件
hydrogen bromide; acetic acid; methoxybenzene T=20°C; 4 h;
参考文献
Qiao, Zongjun; Liu, Hui; Xiao, Xiao; Fu, Yana; Wei, Jianpeng; Li, Yuxue; Jiang, Xuefeng
Organic Letters, 2013 , vol. 15, # 11 p. 2594 - 2597
反应条件
tetrabutyl-ammonium chloride T=60°C; 1 h; Ionic liquid;
参考文献
Monopoli, Antonio; Cotugno, Pietro; Cortese, Marina; Calvano, Cosima Damiana; Ciminale, Francesco; Nacci, Angelo
European Journal of Organic Chemistry, 2012 , # 16 p. 3105 - 3111
反应条件
n-butyl-magnesium bromide in diethyl ether 3 h; Ambient temperature;
参考文献
Babudri, F.; Ciminale, F.; Nunno, L. Di; Florio, S.
Tetrahedron, 1982 , vol. 38, # 4 p. 557 - 561
