6-溴-4-(4-吗啉)喹唑啉合成路线 （共 2 条）
反应条件
in 1,4-dioxane T=150°C; 0.333333 h; Microwave;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2007/103759 A2, 2007 ;
Location in patent: Page/Page column 47 ;
WO 2007/103759 A2
反应条件
1: trichlorophosphate / N,N-dimethyl-formamide / 6 h / |Reflux; |Inert atmosphere 2: isopropyl alcohol / 1 h / |Reflux; |Inert atmosphere View Scheme
参考文献
Shao, Teng; Wang, Juan; Chen, Jian-Gang; Wang, Xiao-Meng; Li, Huan; Li, Yi-Ping; Li, Yan; Yang, Guang-De; Mei, Qi-Bing; Zhang, San-Qi
European Journal of Medicinal Chemistry, 2014 , vol. 75, p. 96 - 105
