2-氨基-5-甲基-4-苯基噻唑合成路线 （共 16 条）
反应条件
in ethanol T=50°C; 0.0833333 h; microwave irradiation;
参考文献
Zhu, Dongjian; Chen, Jiuxi; Xiao, Huilong; Liu, Miaochang; Ding, Jinchang; Wu, Huayue
Synthetic Communications, 2009 , vol. 39, # 16 p. 2895 - 2906
反应条件
N-bromosuccinmide; meta-chloroperoxybenzoic acid in benzene 6 h; Heating;
参考文献
Dahiya, Rajinder; Pujari, H. K.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 966
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.5 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
ammonium acetate on neutral alumina; silica gel in benzene T=80°C; 6 h;
参考文献
Kodomari, Mitsuo; Aoyama, Tadashi; Suzuki, Yoshitada
Tetrahedron Letters, 2002 , vol. 43, # 9 p. 1717 - 1720
反应条件
ammonium acetate on neutral alumina; silica gel in benzene T=80°C; 6 h;
参考文献
Tetrahedron, , vol. 62, # 14 p. 3201 - 3213
反应条件
in dichloromethane; N,N-dimethyl-formamide T=25°C; 12 h; regioselective reaction;
参考文献
Donohoe, Timothy J.; Kabeshov, Mikhail A.; Rathi, Akshat H.; Smith, Ian E. D.
Synlett, 2010 , # 19 p. 2956 - 2958
反应条件
in methanol 1.5 h; Heating;
参考文献
De Kimpe, Norbert; Boelens, Mark; Declercq, Jean-Paul
Tetrahedron, 1993 , vol. 49, # 16 p. 3411 - 3424
反应条件
1: iodine; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dimethyl sulfoxide / 20 °C 2: dichloromethane; N,N-dimethyl-formamide / 12 h / 20 °C View Scheme
参考文献
Organic and Biomolecular Chemistry, , vol. 10, # 5 p. 1093 - 1101
反应条件
1: copper(ll) bromide / ethanol; chloroform; ethyl acetate / 0.5 h / 65 °C 2: ethanol / 2 h / Reflux View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 52, p. 70 - 81
