2-乙酰氨基-3,4,6-三-O-乙酰-2-脱氧-α-D-吡喃葡萄糖酰基氯合成路线 （共 104 条）
反应条件
sodium hydroxide; t-Bu4NBr in dichloromethane
0.75 h; Ambient temperature;
参考文献
Roy, Rene; Tropper, Francois
Synthetic Communications, 1990 , vol. 20, # 14 p. 2097 - 2102
反应条件
1: 7-hydroxy-4-methyl-coumarin With CsOH; tetrabutylammomium bromide in dichloromethane; water
T=20°C; 0.166667 h;
2: 2-Deoxy-2-acetamido-3,4,6-tri-O-acetyl-α-D-glucopyranosyl chloride in dichloromethane; water
0.916667 h;
参考文献
Gold, Henrik; Munneke, Stefan; Dinkelaar, Jasper; Overkleeft, Herman S.; Aerts, Johannes M.F.G.; Codee, Jeroen D.C.; Van Der Marel, Gijs A.
Carbohydrate Research, 2011 , vol. 346, # 12 p. 1467 - 1478
反应条件
potassium peroxodisulfate; thiourea
1.) acetone, 2.) CHCl3, H2O; Yield givenMultistep reaction;
参考文献
Ding, Yili; Miura, Yoshiaki; Etchison, James R.; Freeze, Hudson H.; Hindsgaul, Ole
Journal of Carbohydrate Chemistry, 1999 , vol. 18, # 4 p. 471 - 475
反应条件
1: in acetone
12 h; Heating / reflux;
2: With sodium disulfite in dichloromethane; water
T=20°C; 3 h; Product distribution / selectivity;
参考文献
GENENCOR INTERNATIONAL, INC.; ISIS INNOVATION LTD; THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
Patent: WO2006/55437 A2, 2006 ;
Location in patent: Page/Page column 44; 45; 55 ;
