4-氨基-2-苯并噻唑-2-苯酚合成路线 （共 9 条）
反应条件
polyphosphoric acid T=180°C; 5 h;
参考文献
Santos, Rosane Catarina Dos; Faleiro, Nalva Vivian Da Silva; Campo, Leandra Franciscato; Scroferneker, Maria Lucia; Corbellini, Valeriano Antonio; Rodembusch, Fabiano Severo; Stefani, Valter
Tetrahedron Letters, 2011 , vol. 52, # 23 p. 3048 - 3053
反应条件
1: 80 percent / pyridine 2: 95 percent / SnCl2*2H2O / ethanol / 4 h / Heating 3: 1.) aq. HCl, NaNO2, 2.) aq. NaN3 / 1.) 0-5 deg C, 20 min, 2.) 0-5 deg C, 2 h 4: 5 percent / TFA, TFAA / 1.) 0 deg C, 30 min, 2.) r.t., 18 h View Scheme
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
trifluoroacetic acid; trifluoroacetic anhydride 1.) 0 deg C, 30 min, 2.) r.t., 18 h;
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
1: 95 percent / SnCl2*2H2O / ethanol / 4 h / Heating 2: 1.) aq. HCl, NaNO2, 2.) aq. NaN3 / 1.) 0-5 deg C, 20 min, 2.) 0-5 deg C, 2 h 3: 5 percent / TFA, TFAA / 1.) 0 deg C, 30 min, 2.) r.t., 18 h View Scheme
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
1: 80 percent / pyridine 2: 95 percent / SnCl2*2H2O / ethanol / 4 h / Heating 3: 1.) aq. HCl, NaNO2, 2.) aq. NaN3 / 1.) 0-5 deg C, 20 min, 2.) 0-5 deg C, 2 h 4: 5 percent / TFA, TFAA / 1.) 0 deg C, 30 min, 2.) r.t., 18 h View Scheme
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
1: 1.) aq. HCl, NaNO2, 2.) aq. NaN3 / 1.) 0-5 deg C, 20 min, 2.) 0-5 deg C, 2 h 2: 5 percent / TFA, TFAA / 1.) 0 deg C, 30 min, 2.) r.t., 18 h View Scheme
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
1: polyphosphoric acid / 4 h / 210 °C 2: 1.) aq. HCl, NaNO2, 2.) aq. NaN3 / 1.) 0-5 deg C, 20 min, 2.) 0-5 deg C, 2 h 3: 5 percent / TFA, TFAA / 1.) 0 deg C, 30 min, 2.) r.t., 18 h View Scheme
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
trifluorormethanesulfonic acid; trifluoroacetic acid; trifluoroacetic anhydride 1.) 0 deg C, 30 min, 2.) r.t., 18 h;
参考文献
Stevens, Malcolm F. G.; Shi, Dong-Fang; Castro, Angeles
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1996 , # 1 p. 83 - 94
反应条件
alkali Reduktion des Reaktionsprodukts mit Na2S2O4 in alkal. Loesung;
参考文献
Bogert; Hess
Recueil des Travaux Chimiques des Pays-Bas, 1929 , vol. 48, p. 905
