L-缬氨酰基-L-酪氨酸合成路线 （共 15 条）
反应条件
hydrogen; palladium on activated charcoal in methanol T=25°C; Hydrogenolysis; P=1551.49 Torr; 3 h;
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 4 p. 664 - 674
反应条件
1: 78 percent / Et3N / tetrahydrofuran; H2O / 20 °C 2: H2 / Pd/C / methanol / 3 h / 25 °C / 1551.49 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 4 p. 664 - 674
反应条件
1: 78 percent / Et3N / tetrahydrofuran; H2O / 20 °C 2: H2 / Pd/C / methanol / 3 h / 25 °C / 1551.49 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 43, # 4 p. 664 - 674
反应条件
1: HOBT, dicyclohexylcarbodiimide 2: HF, anisole-thioanisole-o-cresol / 0.5 h / ice-bath View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 8 p. 2507 - 2511
反应条件
1: [125I]-L-Tyrosine in water; acetonitrile 2: Val-NCA in water; acetonitrile T=-10°C; 3 h;
参考文献
Preparative Biochemistry and Biotechnology, , vol. 42, # 6 p. 520 - 534,15
Preparative Biochemistry and Biotechnology, , vol. 42, # 6 p. 520 - 534
反应条件
methanol; palladium on activated charcoal Hydrogenolyse;
参考文献
Helvetica Chimica Acta, , vol. 41, p. 1273,1280
反应条件
methyl-phenyl-thioether; hydrogen fluoride; methoxybenzene; ortho-cresol 0.5 h; ice-bath;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 8 p. 2507 - 2511
反应条件
1: HOBT, dicyclohexylcarbodiimide 2: HF, anisole-thioanisole-o-cresol / 0.5 h / ice-bath View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 28, # 8 p. 2507 - 2511
反应条件
1: aqueous methanol. NaOH 2: HBr; acetic acid View Scheme
参考文献
Helvetica Chimica Acta, , vol. 41, p. 1273,1280
反应条件
1.1: tetrahydrofuran / 60 °C 2.1: water; acetonitrile 2.2: 3407 / 3 h / -10 °C View Scheme
参考文献
Preparative Biochemistry and Biotechnology, , vol. 42, # 6 p. 520 - 534,15
Preparative Biochemistry and Biotechnology, , vol. 42, # 6 p. 520 - 534
