3-苯基-4-氨基丁酸盐酸盐合成路线 （共 6 条）
反应条件
hydrogenchloride; hydrogen; palladium on activated charcoal in isopropyl alcohol T=50°C; P=6840 - 7600 Torr; 3 h;
参考文献
Kreile, D. R.; Slavinskaya, V. A.; Ziemelis, K. M.; Tomsons, U. A.; Gutmanis, A. E.; et al.
J. Appl. Chem. USSR (Engl. Transl.), 1982 , vol. 55, # 4 p. 972 - 974,902 - 904
反应条件
hydrogenchloride; water in water 16 h; Reflux;
参考文献
Biswas, Kallolmay; Gholap, Rajesh; Srinivas, Padakanti; Kanyal, Sachin; Sarma, Koushik Das
RSC Advances, 2014 , vol. 4, # 5 p. 2538 - 2545
反应条件
1.1: cesium fluoride; tetrabutyl-ammonium chloride; bis-triphenylphosphine-palladium(II) chloride / toluene; water / 18 h / 20 °C / |Inert atmosphere 2.1: acetic acid / chloroform / 1 h / 0 - 20 °C 2.2: 20 °C 3.1: trifluoroacetic acid / 1,2-dichloro-ethane / 2 h / 80 °C 4.1: nickel dichloride; sodium tetrahydroborate / methanol; tetrahydrofuran / 1 h / 0 - 20 °C 5.1: hydrogenchloride; water / water / 16 h / |Reflux View Scheme
参考文献
RSC Advances, , vol. 4, # 5 p. 2538 - 2545
反应条件
1: 99 percent / 3 h / Heating 2: 94 percent / Me3SiOTf / 0.5 h / 150 - 155 °C 3: 81 percent / 25percent aq. NH3 / 2 h View Scheme
参考文献
J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979
反应条件
1: 99 percent / 3 h / Heating 2: 61 percent / 0.5 h / 150 - 160 °C 3: 99 percent / H2O View Scheme
参考文献
Kramarova, E. P.; Shipov, A. G.; Orlova, N. A.; Artamkina, O. B.; Belavin, I. Yu.; Baukov, Yu. I.
J. Gen. Chem. USSR (Engl. Transl.), 1988 , vol. 58, # 5 p. 1093 - 1102,970 - 979
反应条件
1: 99 percent / 3 h / Heating
2: 53 percent / 1 h / 150 - 160 °C
View Scheme
参考文献
Kramarova, E. P.; Shipov, A. G.; Orlova, N. A.; Artamkina, O. B.; Belavin, I. Yu.; Baukov, Yu. I.
J. Gen. Chem. USSR (Engl. Transl.), 1988 , vol. 58, # 5 p. 1093 - 1102,970 - 979
