1,3,5-三氨基-2,4,6-三硝基苯合成路线 （共 30 条）
反应条件
ammonia in dichloromethane T=-73°C; 1 h; Yields of byproduct given;
参考文献
Koppes, William M.; Lawrence, G. William; Sitzmann, Michael E.; Adolph, Horst G.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1815 - 1820
反应条件
1: 80percent aq. H2SO4, 90percent aq. nitric acid / 24 h / Ambient temperature 2: 78 percent / 96percent aq. H2SO4, anisole / 0.5 h / Ambient temperature 3: 40 percent / 90percent HNO3, 100percent H2SO4 / 1.) RT, 60 min, 2.) 75 deg C, 90 min 4: 97 percent / anh. ammonia / toluene; CCl4 / 0.58 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 51, # 17 p. 3261 - 3266
反应条件
1: 40 percent / 90percent HNO3, 100percent H2SO4 / 1.) RT, 60 min, 2.) 75 deg C, 90 min 2: 97 percent / anh. ammonia / toluene; CCl4 / 0.58 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 51, # 17 p. 3261 - 3266
反应条件
1: 35 percent / 96percent aq. H2SO4 / 60 h / 0 °C 2: 40 percent / 90percent HNO3, 100percent H2SO4 / 1.) RT, 60 min, 2.) 75 deg C, 90 min 3: 97 percent / anh. ammonia / toluene; CCl4 / 0.58 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 51, # 17 p. 3261 - 3266
反应条件
1: 78 percent / 96percent aq. H2SO4, anisole / 0.5 h / Ambient temperature 2: 40 percent / 90percent HNO3, 100percent H2SO4 / 1.) RT, 60 min, 2.) 75 deg C, 90 min 3: 97 percent / anh. ammonia / toluene; CCl4 / 0.58 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 51, # 17 p. 3261 - 3266
反应条件
1: sulfuric acid; sulfur trioxide; potassium nitrate 2: ammonia / toluene / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 75, # 22 p. 7542 - 7549
反应条件
1: sodium hydroxide / water / 24 h / 30 °C 2: nitric acid / water / -6.7 - 50 °C 3: toluene / 37 - 95 °C / Industry scale; Heating 4: ammonia; methanol / 24 h / -3 - 50 °C / Sealed reactor; Industry scale View Scheme
反应条件
1: sulfuric acid; potassium nitrate / 6 h / 50 - 110 °C 2: 4-amino-1,2,4-(4H)triazole; sodium methylate / dimethyl sulfoxide / 3 h View Scheme
参考文献
Synlett, , vol. 24, # 2 p. 246 - 248
反应条件
1: sulfuric acid <100 percent >; nitric acid / 75 °C 2: ammonia View Scheme
参考文献
Journal of the Chemical Society, , p. 3044
反应条件
potassium hydrogencarbonate; tert-butylamine; trifluoroacetic acid 1.) CH2Cl2, -30 deg C, 2.) room temperature, 15h, 3.) 20 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1815 - 1820
