3-(2-氯苯基)丙酸乙酯合成路线 （共 8 条）
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate 3 h;
参考文献
Berrier, C.; Gesson, J. P.; Jacquesy, J. C.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 23 p. 4973 - 4980
反应条件
1: HCl / diethyl ether / Heating 2: H2 / PtO2 / ethanol View Scheme
参考文献
Orr; Musso; Boswell; Kelley; Joyner; Davis; Baccanari
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3850 - 3856
反应条件
1: 1) piperidine, 2) conc. H2SO4 / 1) pyridine 2: hydrogen / 5percent Pd/C / ethanol View Scheme
参考文献
Berrier, C.; Gesson, J. P.; Jacquesy, J. C.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 23 p. 4973 - 4980
反应条件
1: 94 percent / KOH / ethanol; H2O / 4 h / Ambient temperature 2: 1.) SOCl2, 2.) AlCl3 / 1.) reflux, 12 h; 2.) CH2Cl2, RT, 4 h 3: NaBH4 / methanol / 2 h View Scheme
参考文献
Berrier, C.; Gesson, J. P.; Jacquesy, J. C.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 23 p. 4973 - 4980
反应条件
1: 94 percent / KOH / ethanol; H2O / 4 h / Ambient temperature 2: 1.) SOCl2, 2.) AlCl3 / 1.) reflux, 12 h; 2.) CH2Cl2, RT, 4 h View Scheme
参考文献
Berrier, C.; Gesson, J. P.; Jacquesy, J. C.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 23 p. 4973 - 4980
反应条件
potassium hydroxide in ethanol; water 4 h; Ambient temperature;
参考文献
Berrier, C.; Gesson, J. P.; Jacquesy, J. C.; Renoux, A.
Tetrahedron, 1984 , vol. 40, # 23 p. 4973 - 4980
反应条件
1: LiAlH4 / diethyl ether 2: SOCl2, pyridine 3: aq. ethanol 4: K, NH3 View Scheme
参考文献
Bunnett,J.F.; Skorcz,J.A.
Journal of Organic Chemistry, 1962 , vol. 27, p. 3836 - 3843
反应条件
lithium aluminium tetrahydride; diethyl ether
参考文献
Bunnett,J.F.; Skorcz,J.A.
Journal of Organic Chemistry, 1962 , vol. 27, p. 3836 - 3843
