2,6-二氯-9-(2,3,5-三-O-乙酰基-beta-D-呋喃核糖基)-9H-嘌呤合成路线 （共 15 条）
反应条件
chloro-trimethyl-silane; BnEt3NNO2; sodium nitrite in dichloromethane T=20°C; 1 h;
参考文献
Francom, Paula; Robins, Morris J.
Journal of Organic Chemistry, 2003 , vol. 68, # 2 p. 666 - 669
反应条件
toluene-4-sulfonic acid 0.075 h; microwave irradiation;
参考文献
Qu, Guirong; Liu, Qibin
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 1 p. 196 - 197
反应条件
2-picoline; trichlorophosphate 1 h; Heating;
参考文献
Robins; Uznanski
Canadian Journal of Chemistry, 1981 , vol. 59, # 17 p. 2601 - 2607
反应条件
1: pyridine / dimethylformamide 2: POCl3, N,N-diethyl aniline 3: t-BuONO, SbCl3 / 1,2-dichloro-ethane View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 40, p. 85 - 87
反应条件
1: POCl3, N,N-diethyl aniline 2: t-BuONO, SbCl3 / 1,2-dichloro-ethane View Scheme
参考文献
Journal of Labelled Compounds and Radiopharmaceuticals, , vol. 40, p. 85 - 87
参考文献
US5256650 A1, ;
US 5256650 A
反应条件
chloro-trimethyl-silane; tert.-butylnitrite; 1,1-dibromomethane T=20°C; 3 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 2 p. 666 - 669
反应条件
1: pyridine; H2O / 10 h / Ambient temperature 2: 88 percent / dioxane; H2O / 48 h / Ambient temperature 3: 73 percent / phosporyl chloride, 2-picoline / 1 h / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 59, # 17 p. 2601 - 2607
反应条件
1: 88 percent / dioxane; H2O / 48 h / Ambient temperature 2: 73 percent / phosporyl chloride, 2-picoline / 1 h / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 59, # 17 p. 2601 - 2607
反应条件
1: 1.) m-chloroperoxybenzoic acid; 2.) adenosine deaminase / 1.) aq. acetic acid/dioxane; 2.) pH=7.5, 3 d, room temperature 2: pyridine; H2O / 10 h / Ambient temperature 3: 88 percent / dioxane; H2O / 48 h / Ambient temperature 4: 73 percent / phosporyl chloride, 2-picoline / 1 h / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 59, # 17 p. 2601 - 2607
