1: 43 percent / NaH / dimethylformamide / 100 °C 2: 69 percent / H2 / Pd/C View Scheme

1.1: 78 percent / NaH / dimethylformamide / 3 h / 100 °C 2.1: 96 percent / H2 / Pd/C / methanol / 3.5 h / 20 °C / 760 Torr 3.1: iodine monochloride / methanol / 2 h / 20 °C 3.2: 70 percent / aq. ammonia / methanol View Scheme

sodium hydride in N,N-dimethyl-formamide T=100°C; 3 h;

<b>Multi-step reaction with 2 steps<br /> </b>1: pyridine / 20 &deg;C<br />2: aq. NaOH / methanol / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: pyridine<br />2: NaOH; EtOH<br /> <br /> &nbsp;