4-硝基苯并[c][1,2,5]噻二唑-5-胺合成路线 （共 5 条）
反应条件
potassium hydroxide; hydroxylamine hydrochloride in methanol T=-15 - 20°C;
参考文献
Cillo, Catherine M.; Lash, Timothy D.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 6 p. 955 - 962
反应条件
ammonia in ethylene glycol T=180 - 200°C;
参考文献
Pesin,V.G. et al.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1968 , vol. 4, p. 186 - 188
Khimiya Geterotsiklicheskikh Soedinenii, 1968 , vol. 4, # 2 p. 249 - 253
反应条件
1: potassium hydroxide; aq. sodium hypochlorite / ethanol / 1 h / -10 - 20 °C 2: 67 percent / triethyl phosphite / 1 h / Heating View Scheme
参考文献
Cillo, Catherine M.; Lash, Timothy D.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 6 p. 955 - 962
反应条件
potassium hydroxide; sodium hypochlorite in ethanol T=-10 - 20°C; 1 h; Title compound not separated from byproducts;
参考文献
Cillo, Catherine M.; Lash, Timothy D.
Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 6 p. 955 - 962
反应条件
sodium dithionite in water
Heating;
参考文献
da Silva Miranda, Fabio; Signori, Aline Maria; Vicente, Juliano; de Souza, Bernardo; Priebe, Jacks Patrick; Szpoganicz, Bruno; Goncalves, Norberto Sanches; Neves, Ademir
Tetrahedron, 2008 , vol. 64, # 22 p. 5410 - 5415
