6-(3-甲氧基苯基)-4,4-二甲基-1H-苯并[d][1,3]噁嗪-2(4h)-酮合成路线 （共 3 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethylene glycol dimethyl ether; water T=85°C; 3 h;
参考文献
Wyeth; Ligand Pharmaceuticals, Inc.
Patent: US6444668 B1, 2002 ;
反应条件
1: 100 percent / tetrahydrofuran / 50 °C 2: sodium carbonate; tetrakis(triphenylphosphine)palladium / 1,2-dimethoxy-ethane; H2O / 3 h / 85 °C View Scheme
参考文献
Zhang, Puwen; Terefenko, Eugene A.; Fensome, Andrew; Wrobel, Jay; Winneker, Richard; Lundeen, Scott; Marschke, Keith B.; Zhang, Zhiming
Journal of Medicinal Chemistry, 2002 , vol. 45, # 20 p. 4379 - 4382
参考文献
Wyeth; Ligand Pharmaceuticals, Inc.
Patent: US6436929 B1, 2002 ;
US 6436929 B1
