1: glycine ethyl ester hydrochloric acid With sodium hydrogencarbonate in 2-methyl tetrahydrofuran; water 0.5 h; Cooling; 2: 2-fluoro-benzoyl chloride in 2-methyl tetrahydrofuran; water T=10°C; Schotten-Baumann reaction; 3 h; Cooling;
参考文献
Chavez, Flavio; Kennedy, Nicole; Rawalpally, Thimma; Williamson, R. Thomas; Cleary, Thomas
Organic Process Research and Development, 2010 , vol. 14, # 3 p. 579 - 584
Chavez, Flavio; Kennedy, Nicole; Rawalpally, Thimma; Williamson, R. Thomas; Cleary, Thomas
Organic Process Research and Development, 2010 , vol. 14, # 3 p. 579 - 584