7-硝基-1,2,3,4-四氢喹啉合成路线 （共 17 条）
反应条件
1: 81 percent / 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / CH2Cl2 / 1 h / 25 °C 2: 27 percent / H2 / Pd/C / methanol / 16 h / 760.05 Torr View Scheme
参考文献
Westaway, Susan M.; Chung, Ying-Kit; Davis, John B.; Holland, Vicky; Jerman, Jeffrey C.; Medhurst, Stephen J.; Rami, Harshad K.; Stemp, Geoffrey; Stevens, Alexander J.; Thompson, Mervyn; Winborn, Kim Y.; Wright, James
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4533 - 4536
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in toluene T=100°C; 1.5 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 17 p. 4533 - 4536
反应条件
potassium carbonate in N,N-dimethyl-formamide T=20°C;
参考文献
Bo, Yunxin Y.; Chakrabarti, Partha P.; Chen, Ning; Doherty, Elizabeth M.; Fotsch, Christopher H.; Han, Nianhe; Kelly, Michael G.; Liu, Qingyian; Norman, Mark Henry; Ognyanov, Vassil I.; Wang, Xianghong; Zhu, Jiawang
Patent: US2003/195201 A1, 2003 ;
US 20030195201 A1
反应条件
1: K2CO3 / dimethylformamide / 20 °C 2: H2 / Pd/C / methanol / 20 °C / 760 Torr View Scheme
参考文献
Westaway, Susan M.; Chung, Ying-Kit; Davis, John B.; Holland, Vicky; Jerman, Jeffrey C.; Medhurst, Stephen J.; Rami, Harshad K.; Stemp, Geoffrey; Stevens, Alexander J.; Thompson, Mervyn; Winborn, Kim Y.; Wright, James
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4533 - 4536
反应条件
1: pyridine 2: platinum; ethyl acetate; methanol / Hydrogenation View Scheme
参考文献
Kulka; Manske
Canadian Journal of Chemistry, 1952 , vol. 30, p. 711,717
反应条件
hydrogenchloride; tin
参考文献
Higuchi, Robert I.; Edwards, James P.; Caferro, Thomas R.; Ringgenberg, Josef D.; Kong, James W.; Hamann, Lawrence G.; Arienti, Kristen L.; Marschke, Keith B.; Davis, Robert L.; Farmer, Luc J.; Jones, Todd K.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 9 p. 1335 - 1340
反应条件
4-(N,N-dimethlyamino)pyridine in dichloromethane
