3,4,4-三甲基-2-环戊烯-1-酮合成路线 （共 18 条）
反应条件
1: SOCl2 / 4 h 2: diethyl ether 3: 1.) boron trifluoride etherate, 2.) 10percent aq. HCl / 1.) CH3NO2, 0 deg C, 30 min, 2.) reflux, 1 h View Scheme
参考文献
Smith,A.B.; Toder,B.H.; Branca,S.J.
Journal of the American Chemical Society, 1981 , vol. 103, p. 1996
反应条件
sulfuric acid T=60°C; 6 h;
参考文献
Motoyoshiya, Jiro; Yazaki, Toshikazu; Hayashi, Sadao
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 735 - 740
反应条件
sodium hydroxide in water 0.5 h; Heating;
参考文献
Cadman, Michael L. F.; Crombie, Leslie; Freeman, Stephen; Mistry, Jayshree
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 11 p. 1397 - 1408
反应条件
sodium hydroxide in water 4 h; Heating;
参考文献
Cadman, Michael L. F.; Crombie, Leslie; Freeman, Stephen; Mistry, Jayshree
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 11 p. 1397 - 1408
反应条件
1: 95 percent / nitrosyl chloride / CHCl3 / 2 h / 0 °C 2: 1.) sodium; 2.) 50percent aq. KOH / 1.) 0 deg C, overnight; 2.) reflux, 4 h View Scheme
参考文献
Greene, Andrew E.; lamsard, Jean-Philippe; Luche, Jean-Louis; Petrier, Christian
Journal of Organic Chemistry, 1984 , vol. 49, # 5 p. 931 - 932
参考文献
Zou, Yunfan; Millar, Jocelyn G.
Synlett, 2010 , # 15 p. 2319 - 2321
反应条件
hydrogenchloride; boron trifluoride diethyl etherate 1.) CH3NO2, 0 deg C, 30 min, 2.) reflux, 1 h; Yield given. Multistep reaction;
参考文献
Smith,A.B.; Toder,B.H.; Branca,S.J.
Journal of the American Chemical Society, 1981 , vol. 103, p. 1996
反应条件
1: 68 percent / K2CO3 / H2O / 0.25 h / Ambient temperature 2: 41 percent / conc. H2SO4 / 6 h / 60 °C View Scheme
参考文献
Motoyoshiya, Jiro; Yazaki, Toshikazu; Hayashi, Sadao
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 735 - 740
反应条件
1: 75 percent / Na / methanol / 24 h / Heating 2: 54 percent / 10percent KOH / methanol / 7 h / Heating 3: 77 percent / H2SO4 / 0.42 h / 90 °C 4: 26 percent / NaOH / H2O / 0.5 h / Heating View Scheme
参考文献
Cadman, Michael L. F.; Crombie, Leslie; Freeman, Stephen; Mistry, Jayshree
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 11 p. 1397 - 1408
反应条件
1: 54 percent / 10percent KOH / methanol / 7 h / Heating 2: 77 percent / H2SO4 / 0.42 h / 90 °C 3: 26 percent / NaOH / H2O / 0.5 h / Heating View Scheme
参考文献
Cadman, Michael L. F.; Crombie, Leslie; Freeman, Stephen; Mistry, Jayshree
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 11 p. 1397 - 1408
