(2E,4E)-2,4-癸二烯酸合成路线 （共 46 条）
反应条件
1: 66 percent / pyridinium chlorochromate / CH2Cl2 / 3 h / low temperature 2: 1) NaH / 1) THF, oil, 2a) room temperature, 3 h, b) 50 deg C, 3 h 3: 70 percent / KOH / methanol / 10 h / Ambient temperature View Scheme
参考文献
Bari; Sattar; Vig; Kumar; Vasisht
Journal of the Indian Chemical Society, 1990 , vol. 67, # 12 p. 995 - 996
反应条件
1: (i) KOH, (ii) /BRN= 2047179/ 2: NaIO4 3: KOH View Scheme
参考文献
Tsuji,J. et al.
Tetrahedron Letters, 1977 , p. 1917 - 1918
反应条件
1: NaIO4 2: KOH View Scheme
参考文献
Tsuji,J. et al.
Tetrahedron Letters, 1977 , p. 1917 - 1918
反应条件
1: aqueous sulfuric acid 2: pyridine / Erhitzen des Reaktionsgemisches View Scheme
参考文献
Crombie et al.
Journal of the Chemical Society, 1955 , p. 1025
反应条件
1: palladium/calcium carbonate; ethyl acetate / Hydrogenation 2: aqueous sulfuric acid 3: pyridine / Erhitzen des Reaktionsgemisches View Scheme
参考文献
Crombie et al.
Journal of the Chemical Society, 1955 , p. 1025
反应条件
sodium hydroxide 0.5 h; Ambient temperaturehydrolysis;
参考文献
Hayakawa, Yoichi; Furihata, Kazuo; Seto, Haruo; Otake, Noboru
Tetrahedron Letters, 1985 , vol. 26, # 29 p. 3471 - 3474
反应条件
sodium hydroxide; sodium dithionite; sodium hydrogencarbonate in water T=90°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Camps, Francisco; Coll, Jose; Guerrero, Angel; Guitart, Josefa; Riba, Magi
Chemistry Letters, 1982 , p. 715 - 718
反应条件
1: sulfuric acid 2: lithium alanate; diethyl ether View Scheme
参考文献
Crombie et al.
Journal of the Chemical Society, 1955 , p. 1025
反应条件
1,1'-carbonyldiimidazole in dichloromethane
1.) 0 deg C, 45 min; 2.) 0 deg C to RT, 14 h;
参考文献
Strunz, George M.; Finlay, Heather J.
Canadian Journal of Chemistry, 1996 , vol. 74, # 3 p. 419 - 432
反应条件
1: NCS, PPh3 / CH2Cl2 / 0.5 h / 0 - 5 °C
2: 1.) PPh3, NCS / 1.) CH2Cl2, 0 deg C, 30 min, 2.) CH2Cl2, RT, 10 min
View Scheme
参考文献
Abarbri, Mohamed; Parrain, Jean-Luc; Cintrat, Jean-Christophe; Duchene, Alain
Synthesis, 1996 , # 1 p. 82 - 86
