2,4-己二炔-1,6-二醇合成路线 （共 39 条）
反应条件
potassium hydroxide in tetrahydrofuran; water T=-15°C; 3 h;
参考文献
Rubin, Yves; Lin, Sophia S.; Knobler, Carolyn B.; Anthony, John; Boldi, Armen M.; Diederich, Francois
Journal of the American Chemical Society, 1991 , vol. 113, # 18 p. 6943 - 6949
参考文献
Gao, Kunxiu; Goroff, Nancy S.
Journal of the American Chemical Society, 2000 , vol. 122, # 38 p. 9320 - 9321
反应条件
in toluene 24 h; Heating1 equiv. of benzyl isocyanide;
参考文献
Bertault, Marcel; Canceill, Josette; Collet, Andre; Toupet, Loic
Journal of the Chemical Society, Chemical Communications, 1988 , # 3 p. 163 - 166
反应条件
1: 1,6-dihydroxy-2,4-hexadiyne With sodium hydride in tetrahydrofuran
1 h; Heating;
2: methyl iodide in tetrahydrofuran
4 h; Heating; Further stages.;
参考文献
Varela, Jesus A.; Castedo, Luis; Maestro, Miguel; Mahia, Jose; Saa, Carlos
Chemistry - A European Journal, 2001 , vol. 7, # 23 p. 5203 - 5213
参考文献
Armitage; Whiting
Journal of the Chemical Society, 1952 , p. 2005,2009
反应条件
diisobutylaluminium hydride in dichloromethane
T=0°C;
参考文献
Naruta, Yoshinori; Nagai, Naoshi; Yokota, Tadafumi; Maruyama, Kazuhiro
Chemistry Letters, 1986 , p. 1185 - 1188
反应条件
pyridine
T=100°C; 5 h;
参考文献
Deaton, Kimberly R.; Gin, Mary S.
Organic Letters, 2003 , vol. 5, # 14 p. 2477 - 2480
反应条件
triethylamine in tetrahydrofuran; dichloromethane
T=20°C; 18 h; Inert atmosphere;
参考文献
Morton, Daniel; Leach, Stuart; Cordier, Christopher; Warriner, Stuart; Nelson, Adam
Angewandte Chemie - International Edition, 2009 , vol. 48, # 1 p. 104 - 109
反应条件
triethylamine in diethyl ether
参考文献
Taniguchi, Shin-Ichi; Yokoi, Toshihiro; Izuoka, Akira; Matsushita, Michio M.; Sugawara, Tadashi
Tetrahedron Letters, 2004 , vol. 45, # 12 p. 2671 - 2675
