T=135°C; 4 h;

in toluene 5 h; Ambient temperature;

trichlorophosphate

T=100°C;

1.1: methanesulfonic acid; phosphorous pentoxide / 4 h / 40 °C 2.1: methanol; potassium acetate / 0.25 h / Reflux 3.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 12 h / 20 °C 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 4.2: -78 - 20 °C / Inert atmosphere 5.1: tetrabutyl ammonium fluoride; water / ethyl acetate / 0.17 h / 20 °C 6.1: 10 palladium on activated charcoal; hydrogen; ethylenediamine / methanol / 1 h / 20 °C / 760.05 Torr View Scheme

1.1: methanesulfonic acid; phosphorous pentoxide / 4 h / 40 °C 2.1: methanol; potassium acetate / 0.25 h / Reflux 3.1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 12 h / 20 °C 4.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere 4.2: -78 - 20 °C / Inert atmosphere 5.1: quinoline; hydrogen / hexane; toluene / 1 h / 20 °C / 760.05 Torr 5.2: 0.25 h / 20 °C View Scheme

1: methanesulfonic acid; phosphorous pentoxide / 4 h / 60 °C / Inert atmosphere 2: water; sodium acetate / methanol / 2 h / Reflux 3: potassium carbonate / acetone / 2 h / Inert atmosphere; Reflux View Scheme

sodium tetrahydroborate in ethanol T=0°C; Inert atmosphere;

暂无反应条件数据

aluminium trichloride T=100°C;