1-(2,6-二氯苯基)-1,3-二氢-5-羟基-2H-吲哚-2-酮合成路线 （共 13 条）
反应条件
1: 62 percent / TiCl4 / toluene / 48 h / 20 °C 2: (CH3CH2)3N / dimethylformamide / 6 h / 110 °C 3: toluene; propan-2-ol / 4 h / 80 - 100 °C 4: 18 percent / AlCl3 / 4 h / 200 - 215 °C View Scheme
参考文献
Graevskaya; Azimov; Ryabova; Alekseeva; Anisimova; Syubaev; Granik
Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 1 p. 41 - 44
反应条件
1: (CH3CH2)3N / dimethylformamide / 6 h / 110 °C 2: toluene; propan-2-ol / 4 h / 80 - 100 °C 3: 18 percent / AlCl3 / 4 h / 200 - 215 °C View Scheme
参考文献
Graevskaya; Azimov; Ryabova; Alekseeva; Anisimova; Syubaev; Granik
Pharmaceutical Chemistry Journal, 1998 , vol. 32, # 1 p. 41 - 44
反应条件
potassium hydroxide; sodium hydroxide in butan-1-ol 24 h; Heating; Yield given;
参考文献
Wang, Jian Ta; Wang, Ying; Zhang, Ji Quan; Cui, Xing; Zhang, Yi; Zhu, Gao Feng; Tang, Lei
Chinese Chemical Letters, 2011 , vol. 22, # 4 p. 409 - 412
