6-巯嘌呤-9-beta-D-呋喃核糖苷2',3',5'-三乙酸酯合成路线 （共 9 条）
反应条件
molecular sieve; potassium chloride T=100°C; 3.5 h;
参考文献
Sa, Marcus Mandolesi; Meier, Lidiane
Synlett, 2006 , # 20 p. 3474 - 3478
反应条件
N,O-bis-(trimethylsilyl)-acetamide; tin(IV) chloride in 1,2-dichloro-ethane T=60°C; Vorbruggen nucleosidation reaction; 3 h; Inert atmosphere;
参考文献
Ellermann, Manuel; Paulini, Ralph; Jakob-Roetne, Roland; Lerner, Christian; Borroni, Edilio; Roth, Doris; Ehler, Andreas; Schweizer, W. Bernd; Schlatter, Daniel; Rudolph, Markus G.; Diederich, Francois
Chemistry - A European Journal, 2011 , vol. 17, # 23 p. 6369 - 6381
反应条件
thiourea in ethanol 1 h; Heating;
参考文献
Meier, Lidiane; Monteiro, Gustavo C.; Baldissera, Rodrigo A.M.; Sa, Marcus Mandolesi
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 859 - 866
反应条件
1: 95 percent / dimethyldioxirane, NH3 / acetone; CH2Cl2 / 25 °C 2: 83 percent / 2N methanol. NH3 / 25 °C View Scheme
参考文献
Saladino, Raffaele; Crestini, Claudia; Bernini, Roberta; Frachey, Giuseppe; Mincione, Enrico
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 21 p. 3053 - 3054
反应条件
1: 55 percent / dimethyldioxirane / acetone; CH2Cl2 / 25 °C 2: 87 percent / 2N methanol. NH3 / 25 °C View Scheme
参考文献
Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio
Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780
反应条件
ammonia; oxygen; ozone in dichloromethane T=0°C; 0.0833333 h;
参考文献
Saladino, Raffaele; Mincione, Enrico; Crestini, Claudia; Mezzetti, Maurizio
Tetrahedron, 1996 , vol. 52, # 19 p. 6759 - 6780
反应条件
methanol; water; triethylamine T=71°C; Microwave irradiation;
参考文献
Meier, Lidiane; Monteiro, Gustavo C.; Baldissera, Rodrigo A.M.; Sa, Marcus Mandolesi
Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 859 - 866
反应条件
nickel in ethanol 4 h; Heating;
参考文献
Shimazaki, Masami; Nakamura, Hikaru; Iitaka, Yoichi; Ohno, Masaji
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3104 - 3112
反应条件
1: 75 percent / Brown's nickel / ethanol / 4 h / Heating 2: 75 percent / 10 h / 0 - 5 °C / Irradiation; with Vycor Filter 3: 88 percent / phenyltrimethylammonium perbromide / methanol / 0.17 h 4: 50 percent / K2CO3 / acetone / 24 h / Ambient temperature 5: 57 percent / NaI / acetone / 4 h / Ambient temperature 6: 88 percent / NaBH4 / methanol / 0.25 h / Ambient temperature 7: 75 percent / satd. NH3/MeOH / 2 h / Ambient temperature View Scheme
参考文献
Shimazaki, Masami; Nakamura, Hikaru; Iitaka, Yoichi; Ohno, Masaji
Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 9 p. 3104 - 3112
