2-溴-3-甲基-2-丁烯合成路线 （共 36 条）
反应条件
diethyl ether; lithium
und anschliessend mit Kohlendioxid;
参考文献
Braude; Evans
Journal of the Chemical Society, 1955 , p. 3337,3339
反应条件
lithium
1) THF, -30 deg C, 1,5 h, 2) THF, -78 deg C to 0 deg C; Yield given. Multistep reaction;
参考文献
Hoffmann, H. M. R.; Haase, Klaus; Ismail, Zeinhom M.; Preftitsi, Stamatia; Weber, Anette
Chemische Berichte, 1982 , vol. 115, # 12 p. 3880 - 3885
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran
T=60°C;
参考文献
Mori, Hajime; Ikoma, Keiichi; Katsumura, Shigeo
Chemical Communications, 1997 , # 22 p. 2243 - 2244
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; tetrakis(triphenylphosphine) palladium(0); n-butyllithium; zinc(II) chloride
1.) THF, hexane, -78 deg C, 1.5 h; -78 deg C to 0 deg C; 0 deg C, 3 h, 2.) 65 deg C, 33 h; Yield givenMultistep reaction;
参考文献
Mori, Hajime; Ikoma, Keiichi; Isoe, Sachihiko; Kitaura, Kazuo; Katsumura, Shigeo
Journal of Organic Chemistry, 1998 , vol. 63, # 24 p. 8704 - 8718
反应条件
1: 2-bromo-3-methyl-2-butene With lithium in tetrahydrofuran
T=20°C; 2 h;
2: (E)-2-Methoxy-3,5-dimethyl-1-morpholin-4-yl-hex-2-en-1-one in tetrahydrofuran
T=-78°C; 2 h;
参考文献
Bee, Cisco; Leclerc, Eric; Tius, Marcus A.
Organic Letters, 2003 , vol. 5, # 26 p. 4927 - 4930
参考文献
Ipatjew
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1895 , vol. 27, p. 360;
Chemische Berichte, 29 Ref. <1896>,90
