2-甲基-1,10-菲啰啉合成路线 （共 14 条）
反应条件
in diethyl ether adding N-N'-ligand (30percent excess) to soln./suspension of PtCl(CH3)(Me2S)2 in diethyl ether, stirring (room temp., 6 h); evapg., adding diethyl ether to residue, stirring (6 h), evapg., adding diethyl ether, stirring (6 h), evapg., crystn. (methylen chloride - diethyl ether);
参考文献
Cucciolito, Maria Elena; Felice, Vincenzo De; Panunzi, Achille; Vitagliano, Aldo
Organometallics, 1989 , vol. 8, p. 1180 - 1187
反应条件
in diethyl ether adding N-N'-ligand (30percent molar excess) to soln./suspn. of dimethyl sulfide complex (in diethyl ether), stirring under ethylene (atmospheric pressure, 15 h, room temp.), pptn.; filtering, drying, recrystn. (methylene chloride - diethyl ether);
参考文献
Cucciolito, Maria Elena; Felice, Vincenzo De; Panunzi, Achille; Vitagliano, Aldo
Organometallics, 1989 , vol. 8, p. 1180 - 1187
反应条件
selenium(IV) oxide in 1,4-dioxane 2 h; Reflux;
参考文献
Zhang, Min; Gao, Rong; Hao, Xiang; Sun, Wen-Hua
Journal of Organometallic Chemistry, 2008 , vol. 693, # 26 p. 3867 - 3877
反应条件
1: in 2,2,2-trifluoroethanol
T=30°C; Diels-Alder reaction;
2: With hydrogenchloride; oxygen in water; acetonitrile
P=760.051 Torr; 16 h;
参考文献
De, Kavita; Legros, Julien; Crousse, Benoit; Chandrasekaran, Srinivasan; Bonnet-Delpon, Daniele
Organic and Biomolecular Chemistry, 2011 , vol. 9, # 2 p. 347 - 350
反应条件
sulfuric acid; sodium iodide
T=110°C; 5 h;
参考文献
Belser, Peter; Bernhard, Stefan; Guerig, Urs
Tetrahedron, 1996 , vol. 52, # 8 p. 2937 - 2944
反应条件
in tetrahydrofuran; diethyl ether
T=20°C;
参考文献
Poole, Robert A.; Bobba, Gabriella; Cann, Martin J.; Frias, Juan-Carlos; Parker, David; Peacock, Robert D.
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 6 p. 1013 - 1024
反应条件
sodium hydroxide in isopropyl alcohol
12 h; Reflux;
参考文献
Visniakova; Zilinskas; Tumkevicius
Chemistry of Heterocyclic Compounds, 2012 , vol. 48, # 6 p. 943 - 949
Khim. Geterotsikl. Soedin., 2012 , # 6 p. 1013 - 1020,8
反应条件
potassium hydroxide in ethanol
Friedlaender reaction; 8 h; Heating;
参考文献
Rahman, A.F.M. Motiur; Kwon, Youngjoo; Jahng, Yurngdong
Heterocycles, 2005 , vol. 65, # 11 p. 2777 - 2782
反应条件
1: diethyl ether; tetrahydrofuran / 2.5 h / 0 - 10 °C / 1 eq. MeLi
2: KMnO4 / acetone
View Scheme
参考文献
Pijper; Van der Goot; Timmerman; Nauta Th.
European Journal of Medicinal Chemistry, 1984 , vol. 19, # 5 p. 399 - 404
反应条件
diarsenic pentoxide; sulfuric acid
T=140°C;
参考文献
Irving et al.
Journal of the Chemical Society, 1953 , p. 3417,3424
