1: With palladium diacetate in toluene 2: With tri-tert-butyl phosphine in toluene T=75°C; 1 h; 3: With sodium t-butanolate in tetrahydrofuran; toluene T=75 - 80°C; 3.5 h; Product distribution / selectivity;
1: With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 1 h; 2: With boric acid trimethyl ester in tetrahydrofuran; hexane T=-30°C; 0.25 h; 3: With hydrogenchloride in tetrahydrofuran; hexane; water