1-甲基-2,3,4,9-四氢-1H-吡啶并[3,4-b]吲哚-6-醇合成路线 （共 7 条）
反应条件
in water T=36.5°C; 72 h;
参考文献
Somei, Masanori; Seto, Minoru
Heterocycles, 2003 , vol. 60, # 3 p. 519 - 522
反应条件
in water T=-10°C; 0.5 h; pH 10.8; Yield given;
参考文献
Zhang; Goyal; Blank; Dryhurst
Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 82 - 93
反应条件
in water T=36.5°C; 24 h;
参考文献
Somei, Masanori; Seto, Minoru
Heterocycles, 2003 , vol. 60, # 3 p. 519 - 522
反应条件
1: H2O / 12 h / 37 °C / pH 4.2 2: H2O / 0.5 h / -10 °C / pH 10.8 View Scheme
参考文献
Zhang; Goyal; Blank; Dryhurst
Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 82 - 93
反应条件
acetate buffer 48 h; Ambient temperature;
参考文献
Burov, Yu. V.; Zagorevskii, V. A.; Zhukov, V. N.; Novikova, N. N.; Silenko, I. D.
Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 8 p. 559 - 563
Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 8 p. 936 - 940
反应条件
potassium fluoride in methanol 4 h; Heating; Product distribution; Further Variations:ReagentsSolventsTemperaturestime;
参考文献
Somei, Masanori; Seto, Minoru
Heterocycles, 2003 , vol. 60, # 3 p. 519 - 522
反应条件
water 0.333333 h; electrochemical oxidation (+1.0 V), pH 1.5;
参考文献
Journal of Medicinal Chemistry, , vol. 35, # 1 p. 82 - 93
