N-乙氧羰基-4-哌啶酮合成路线 (共 74 条)
反应条件
1: ethanol / 4 h / 100 °C
2: potassium hydroxide; water / ethanol / |Reflux
View Scheme
参考文献
Rosini, Michela; Simoni, Elena; Bartolini, Manuela; Soriano, Elena; Marco-Contelles, Jose; Andrisano, Vincenza; Monti, Barbara; Windisch, Manfred; Hutter-Paier, Birgit; Mcclymont, David W.; Mellor, Ian R.; Bolognesi, Maria Laura
ChemMedChem, 2013 , vol. 8, # 8 p. 1276 - 1281
反应条件
sodium tetrahydroborate; molecular sieve
1) benzene, reflux, 20 h; 2) EtOH, room temp., 5 h; Yield given. Multistep reaction;
参考文献
Domany; Barta-Szalai; Palosi; Szabo; Schon
Arzneimittel-Forschung/Drug Research, 1994 , vol. 44, # 9 p. 989 - 991
反应条件
toluene-4-sulfonic acid in benzene
参考文献
Tetzlaff, Claus; Vilsmaier, Elmar; Schlag, Wolf-Ruediger
Tetrahedron, 1990 , vol. 46, # 24 p. 8117 - 8130
反应条件
1: 92 percent / ethanol / 3.25 h / Ambient temperature
2: 57 percent / tert-BuOK / xylene / 6 h / Heating
View Scheme
参考文献
Iamanishi, Takeshi; Shin, Hiroaki; Hanaoka, Miyoji; Momose, Takefumi; Imanishi, Ichiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 10 p. 3617 - 3623