3,4,5,6-四氟苯-1,2-二胺合成路线 （共 13 条）
反应条件
CaCl2 in diethyl ether; ethanol
参考文献
The State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University; The University of Oregon; The Regents of the University of California
Patent: US5514680 A1, 1996 ;
US 5514680 A
反应条件
1: 66 percent / NH3 / diethyl ether / 18 h / Ambient temperature 2: 64 percent / SnCl2, conc. aq. HCl / ethanol / 0.5 h / Heating View Scheme
参考文献
Brooke,G.M. et al.
Journal of the Chemical Society, 1961 , p. 802 - 807
反应条件
1: aq. H2O2, (CF3CO)2O / CH2Cl2 / Heating 2: NH3 / diethyl ether / Ambient temperature 3: H2 / Raney-Ni / ethanol View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
反应条件
1: aq. H2SO4 / Heating 2: H2 / Raney-Ni / ethanol View Scheme
参考文献
Belf,L.J. et al.
Tetrahedron, 1967 , vol. 23, p. 4719 - 4727
反应条件
1: aq. HNO3, H2SO4 2: aq. H2SO4 / Heating 3: H2 / Raney-Ni / ethanol View Scheme
参考文献
Belf,L.J. et al.
Tetrahedron, 1967 , vol. 23, p. 4719 - 4727
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
反应条件
ammonium hydroxide; copper(I) bromide T=120°C; 48 h; Further byproducts given;
参考文献
Selivanova; Pokrovskii; Shteingarts
Russian Journal of Organic Chemistry, 2001 , vol. 37, # 3 p. 404 - 409
反应条件
1: H2O 2: 1,4-dioxane 3: HI View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
反应条件
1: HI 2: 1,4-dioxane 3: HI View Scheme
参考文献
Gmelin Handbook: F: PerFHalOrg.7, 1, page 1 - 84
反应条件
acetic acid; sodium nitrite T=70°C; 0.5 h;
参考文献
Heaton, Alan; Hill, Mark; Drakesmith, Frederick
Journal of Fluorine Chemistry, 1997 , vol. 81, # 2 p. 133 - 138
