4-(2-苯基-1-乙炔)苯甲腈合成路线 （共 64 条）
反应条件
copper(l) iodide; diethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride
T=20°C; 30 h;
参考文献
Fuji, Koji; Morimoto, Tsumoru; Tsutsumi, Ken; Kakiuchi, Kiyomi
Chemical Communications, 2005 , # 26 p. 3295 - 3297
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in dimethyl sulfoxide
T=90°C; 12 h;
参考文献
Pyo, Ayoung; Kim, Ji Dang; Choi, Hyun Chul; Lee, Sunwoo
Journal of Organometallic Chemistry, 2013 , vol. 724, p. 271 - 274
反应条件
(4R,5R)-DIOP; palladium diacetate; copper(l) chloride in N,N-dimethyl-formamide
T=20 - 120°C; Sila-Sonogashira cross-coupling reaction;
参考文献
Nishihara, Yasushi; Inoue, Eiji; Noyori, Shintaro; Ogawa, Daisuke; Okada, Yoshiaki; Iwasaki, Masayuki; Takagi, Kentaro
Tetrahedron, 2012 , vol. 68, # 24 p. 4869 - 4881
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide
Ambient temperature;
参考文献
Gujadhur, Rattan K.; Bates, Craig G.; Venkataraman
Organic Letters, 2001 , vol. 3, # 26 p. 4315 - 4317
反应条件
pyridine; CuCl2·2H2O; triethylamine; p-benozquinone in dichloromethane
T=20°C; 12 h; Schlenk technique;
参考文献
Shi, Leilei; Jia, Wei; Li, Xun; Jiao, Ning
Tetrahedron Letters, 2013 , vol. 54, # 15 p. 1951 - 1955
反应条件
bis-triphenylphosphine-palladium(II) chloride; ammonium hydroxide; copper(l) iodide in tetrahydrofuran
T=20°C; Sonogashira coupling; 6 h;
参考文献
Mohamed Ahmed, Mohamed S.; Sekiguchi, Akitoshi; Masui, Kentaro; Mori, Atsunori
Bulletin of the Chemical Society of Japan, 2005 , vol. 78, # 1 p. 160 - 168
反应条件
N-ethyl-N,N-diisopropylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in water; isopropyl alcohol
T=100°C; 0.25 h; Microwave irradiation;
参考文献
Kabalka, George W.; Naravane, Abhijit; Zhao, Li Li
Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7091 - 7093
反应条件
copper(l) chloride; palladium dichloride; tris(p-fluoro phenyl)phosphine in N,N-dimethyl-formamide
T=100°C; sila-Sonogashira-Hagihara cross-coupling; 12 h; Inert atmosphere;
参考文献
Nishihara, Yasushi; Inoue, Eiji; Noyori, Shintaro; Ogawa, Daisuke; Okada, Yoshiaki; Iwasaki, Masayuki; Takagi, Kentaro
Tetrahedron, 2012 , vol. 68, # 24 p. 4869 - 4881
反应条件
tris(dibenzylideneacetone)dipalladium (0); N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=80°C; Stille reaction; 10 h;
参考文献
Shen, Wang; Wang, Le
Journal of Organic Chemistry, 1999 , vol. 64, # 24 p. 8873 - 8879
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; N-ethyl-N,N-diisopropylamine in water; isopropyl alcohol
T=100°C; 0.333333 h; Microwave irradiationInert atmosphere;
参考文献
Coltuclu, Vitali; Dadush, Eric; Naravane, Abhijit; Kabalka, George W.
Molecules, 2013 , vol. 18, # 2 p. 1755 - 1761
