1-(1-环己烯基)哌啶合成路线 （共 44 条）
反应条件
triethylamine in dichloromethane
2 h; Ambient temperature;
参考文献
Pellacani, Lucio; Pulcini, Patrizio; Tardella, Paolo A.
Journal of Organic Chemistry, 1982 , vol. 47, # 25 p. 5023 - 5025
反应条件
1: 59 percent / ethanol / 64 h
2: 100 percent / LiAlH4 / diethyl ether / 3 h / Ambient temperature
3: oxalic acid / dioxane / 6 h / Heating
View Scheme
参考文献
Carlsson, S.; Lawesson, S.-O.
Tetrahedron, 1980 , vol. 36, p. 3585 - 3590
反应条件
1: 1.) bromine, 2.) LDA / 1.) Et2O, -78 deg C, 0.5 h; 2.) Et2O, n-hexane, r.t., 30 min
2: 95 percent / potassium tert-butoxide / diethyl ether / 0.08 h / Ambient temperature
3: 75 percent / 2 N aq. HCl / 24 h / Ambient temperature
View Scheme
参考文献
Henniges; Gussetti; Militzer; Baird; De Meijere
Synthesis, 1994 , # 12 p. 1471 - 1475
反应条件
1: 1.) FeCl3; 2.) 30percent NaOH; 3.) 10percent aq. AcOH / 1.) CH2Cl2, (-70)-0 deg C; 2.) CH2Cl2, 0 deg C, 3 min; 3.) r.t., 4 h
2: 85 percent / aq. 6N HCl / 15 h / Heating
View Scheme
参考文献
Baudoux, Dominique; Fuks, Robert
Bulletin des Societes Chimiques Belges, 1984 , vol. 93, # 11 p. 1009 - 1018
反应条件
1: 99 percent / Molecular sieves / toluene / 20 h / Heating
2: 75 percent / AcOH / H2O / 1.) reflux, 3 h, 2.) room temp., 12 h
View Scheme
参考文献
Katritzky, Alan R.; El-Mowafy, Azzahra M.; Musumarra, Giuseppe; Sakizadeh, Kumars; Sana-Ullah, Choudhry; et al.
Journal of Organic Chemistry, 1981 , vol. 46, # 19 p. 3823 - 3830
反应条件
boron trifluoride diethyl etherate in dichloromethane
参考文献
Takazawa, Osamu; Kogami, Kunio; Hayashi, Kazuo
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 7 p. 1876 - 1881
反应条件
benzoyl chloride in chloroform
12 h; Heating;
参考文献
Klemm, L. H.; Muchiri, Daniel R.; Louris, John N.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, p. 1135 - 1140
反应条件
triethylamine in dichloromethane
2 h; Ambient temperature;
参考文献
Pellacani, Lucio; Pulcini, Patrizio; Tardella, Paolo A.
Journal of Organic Chemistry, 1982 , vol. 47, # 25 p. 5023 - 5025
反应条件
1: 33 percent / Et3N / CH2Cl2 / 2 h / Ambient temperature
2: 2 N HCl / 105 °C / overnight
View Scheme
参考文献
Pellacani, Lucio; Pulcini, Patrizio; Tardella, Paolo A.
Journal of Organic Chemistry, 1982 , vol. 47, # 25 p. 5023 - 5025
反应条件
triethylamine in chloroform
Heating;
参考文献
Xu, Fan; Cao, Xueqin; Cao, Zhengbai; Zou, Lei
Tetrahedron Letters, 2000 , vol. 41, # 52 p. 10257 - 10261
