反应条件
1: 3,3-dimethyl-cyclohexanone With lithium diisopropyl amide in tetrahydrofuran
T=-78°C; 2 h;
2: N,N-bis(trifluoromethanesulfonyl)aniline in tetrahydrofuran
T=-78 - 0°C; 3 h;
3: vinyl-tributylstannane With tetrakis(triphenylphosphine) palladium(0); lithium chloride in tetrahydrofuran
36 h; Reflux;
参考文献
Liu, Weiguo; Zhou, Jinming; Geng, Guoyan; Shi, Qingwen; Sauriol, Francoise; Wu, Jian Hui
Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 971 - 975